Advisory Board and Editors Systems Biology
Jürg Bähler
Jürg Bähler is a Professor of Systems Biology at University College London. His laboratory studies genome regulation during cellular proliferation, quiescence, and ageing using fission yeast (Schizosaccharomyces pombe) as a model system. They apply multiple genetic, computational and genome-wide approaches for systems-level understanding of regulatory processes and complex relationships between genotype, phenotype, and environment, including roles of genome variation and evolution, transcriptome regulation, and non-coding RNAs.
Jürg Bähler is an elected Member of the European Molecular Biology Organisation (EMBO) and a Fellow of the Royal Society of Biology, and he received a Wellcome Trust Senior Investigator Award and a Royal Society Wolfson Research Merit Award.
Shawn M Gomez
Professor and Associate Chair for Research in the Joint Department of Biomedical Engineering at UNC-CH and NCSU and Professor in the Department of Pharmacology at UNC-CH. Previous Florence Gould Scholar and Pasteur Foundation Fellow. Current research interests in systems and synthetic biology, bioimage informatics, and network science applied to biology. Broader interests in translational medicine and the fostering of innovative solutions to problems in healthcare.
Noriko F Hiroi
Noriko Hiroi is Assistant Professor of the Department of Biosciences and Informatics, Keio University. She started to develop her career in Molecular Biology and Biochemistry, and currently works in Systems Biology and Quantitative Biology area. Her research interest includes in vivo oriented modelling, molecular mechanisms of higher-functions of central nerve systems, microfluidics technology and optical technologies and informatics for bioimaging.
Dezső Módos
I am a medical doctor and a systems biologist. During my scientific carrier, I have tried to understand diseases and find novel approaches to treat them with drugs, whether it is cancer or UC. I finished the Semmelweis University Doctor of Medicine course on 2012 and then started my PhD in network biology. I was involved in developing multiple biological network databases transcription factor-target layers such as SignaLink, AutophagyRegulatory Network or the NRF2Ome. My main project was to understand signalling networks in cancer and how the different paralogues of a protein can act in the signalling network.
Since then I have been a Postdoctoral Research Associate at Cambridge University, where my main focus was how can we use networks to predict mechanisms of action of compound combinations. I used various chemical informatics techniques besides network biology such as chemical fingerprints, machine learning and gene expression-based toxicity prediction.
Currently, I am working at the Earlham Institute and Quadram Institut in Norwich researching inflammatory bowel disease and using network biology to decipher the pathogenesis of complex disorders.
I have recently moved to Imperial College, London to go through the therapeutic celling in IBD using systems biology.
Christopher J Mungall
I am a Computer Research Scientist in the Environmental Genomics and Systems Biology division at Lawrence Berkeley Laboratory. My work focuses on computational methods for representing and interpreting complex biological data, in particular through the development and application of knowledge representation structures such as ontologies.
Hamed S. Najafabadi
Assistant Professor of Human Genetics at McGill University, Canada Research Chair in Systems Biology of Gene Regulation. Studying the mechanisms of transcriptional and post-transcriptional gene regulation and their role in human diseases.
Vera Pancaldi
I was trained as a physicist at Imperial College London and soon found my way in systems and computational biology. Since 2018 I lead a computational biology team at the Cancer Research Center of Toulouse (CRCT) working on modelling cancer and its interactions with the immune system.
I have worked on various projects on stress response in fission yeast and prediction of protein interactions (in the group of Jurg Bahler at Sanger Institute/University College London), epigenomics and hybrid vigour in plants (with David Baulcombe at Cambridge University) and integrative epigenomics in cancer (with Alfonso Valencia at CNIO, Madrid and Barcelona Supercomputing Center). My main current focus is understanding the relationship between genome architecture and heterogeneity at various levels and relating heterogeneity of tumour infiltrating immune cells to patient's prognoses in different cancers. I also co-founded Cambridge Networks Network in 2011, an online forum for scientists interested in networks in Cambridge in beyond.
Thiago Parente
Scientist in Public Health at the Laboratory of Functional Genomics and Bioinformatics at the Oswaldo Cruz Institute (IOC, Fiocruz), Rio de Janeiro, Brazil. Scientific coordinator of the Institutional Bioinformatics Platform. CNPq Level 2 Research Productivity Scholar (Genetics). Permanent professor at the Graduate program on Systems and Computational Biology IOC, Fiocruz. Graduated in Biological Sciences - Genetics major - from the Federal University of Rio de Janeiro (2006), with a Master's degree in Cell and Molecular Biology from the IOC (2008) and PhD in Biophysics from UFRJ (2012). Through high performance technologies for DNA sequencing and computational data analysis, I investigate the effects of pollution on fauna, using fish as model organisms, and their responses and genetic adaptations to pollutants, especially those involved in the xenobiotic biotransformation system.
Eike Staub
TU Braunschweig & Uni Glasgow. Metagen Gesellschaft für Genomforschung mbH.
Max Planck Institute for Molecular Genetics. Altana Pharma AG. And currently Merck Healthcare KGaA
My speciality areas are Computational Biology, Systems Biology, Oncogenomics, Drug Target Identification, Biomarker Research.
Jiyang Yu
Dr. Jiyang Yu's research is focused on systems biology, systems immunology, single-cell systems biology, immuno-oncology, translational oncology and functional genomics. He earned his bachelor’s degree in Computer Science from Zhejiang University, China. In 2008-2012, he was trained in Dr. Andrea Califano’s laboratory at Columbia University and earned his PhD degree in Biomedical Informatics.