Researching the assembly of cell surface appendages in archaea and their role in adhesion and biofilm formation. The model organism we study is the hyperthermophilic archaeon Sulfolobus acidocaldarius. We use genetic approaches to identify systems in Sulfolobus that are involved in the assembly of cell surface appendages and biochemically characterize the subunits and their interplay in the assembly process.
Kathryn Ball trained as an enzymologist and protein biochemist. She was awarded a Broodbank Fellowship (University of Cambridge) and was the first CRUK Senior Cancer Research Fellow (University of Dundee). She moved to the University of Edinburgh in 2004 where she is the Professor of Biochemistry and Cell Signalling. Her current research is focused on protein structure function analysis and the mechanisms underlying the regulation of protein function by ubiquitin in human health and disease.
Group Leader, Structural Biochemistry in Institute of Complex Systems (ICS-6) in Research Centre Juelich, Germany. Postdoctoral scientist at the Max Planck Institute for Medical Research, Heidelberg, Germany (1996-1999) and at Columbia University, New York, USA (1999-2002). Primary focus of my research is to understand the structure-function relationships of soluble and membrane proteins of biological importance.
Assistant Professor of Integrative Biology and Pharmacology at University of Texas Medical School at Houston. Member of the Graduate School of Biomedical Sciences program (UT Houston). Expertise in kinase-mediated cell signaling, transcriptional regulation, skeletal muscle and hepatic metabolism and muscle regeneration.
Buchanan Professor of Genetics at the University of Edinburgh & a Fellow of the Royal Societies of London & Edinburgh. Director of the Wellcome Trust Centre for Cell Biology from 1999 to 2011. Governor of the Wellcome Trust from 2000-10 & Deputy Chairman from 2007. Currently trustee of Cancer Research UK & the Kirkhouse Trust. Awards include Howard Hughes International Fellowship, the Louis-Jeantet Prize for Medicine, the Gairdner Foundation prize and the Gabor & GSK Medals of the Royal Society.
Max Planck Research Group Leader since 2014; assistant professor at Radboud University Nijmegen; PostDocs at University of Leuven and University of Strasbourg; PhD in Biophysics from Ludwig Maximilian University Munich; Research interests: mechanobiology, molecular force sensors, protein engineering, single molecule techniques (force and fluorescence); Editor of Biophysical Reviews and Letters
2011-:Schools of Cellular & Molecular Medicine and Biochemistry, University of Bristol: Reader in Microbiology.
2007-2011: as above, Senior Lecturer in Microbiology.
2001-2007: Dunn School of Pathology, University of Oxford: Guy Newton Senior Research Fellow.
1997-2000: Institute Pasteur, Paris: Postdoctoral fellow.
1996: EMBL, Heidelberg: Postdoctoral fellow.
1991-1995: EMBL, Heidelberg: PhD in Cell Biology
1988-1991: University College, London: B. Sc. in Genetics, 1st class.
Personal Chair in Electron Microscopy and Image Processing, of Biological Complexes, at the University of Edinburgh
Vania Braga's research interests include understanding the signalling pathways required for epithelial specification and how these processes are subverted during diseases and tumour progression. She is Deputy-Head of the Molecular Medicine Section, and was appointed Campus Director for the Faculty of Medicine (2012-2015). Dr. Braga participates in a number of editorial boards, review panels and grant committees in Europe.
Inserm Researcher in the field of Cardiovascular Research, currently focusing on therapeutic angiogenesis with polymer-based targeted growth factor delivery.
PhD in Tumor Biology (Pr Yihai Cao, Karolinska Institutet, Sweden), and expertise in Adipose tissue angiogenesis. Postdoc at UCLA (Pr Lily Wu) in molecular imaging and tumor lymphangiogenesis field.
Member of European Vascular Biology Organisation, French society for Cardiovascular Research, French society for Angiogenesis Research.
Associate Professor of Anesthesiology at University of Rochester Medical Center. PhD in Biochemistry from Cambridge University (UK) and post-doctoral training at the University of Alabama at Birmingham. Research program in mitochondria, cardiac ischemia, and cardioprotective therapies.
Sarah Butcher did her PhD in EMBL Heidelberg, mentored by Stephen Fuller and Helen Saibil, she carried out postdoctoral training in the MRC Virology Unit in Glasgow, before moving to Helsinki University where she is currently Programme Director of the Structural Biology and Biophysics Programme, Institute of Biotechnology, Head of Instruct-FI National Affiliate Center, Finland & Head of National cryoEM facility. She works on macromolecular structure and assembly, especially of viruses.