Researching the assembly of cell surface appendages in archaea and their role in adhesion and biofilm formation. The model organism we study is the hyperthermophilic archaeon Sulfolobus acidocaldarius. We use genetic approaches to identify systems in Sulfolobus that are involved in the assembly of cell surface appendages and biochemically characterize the subunits and their interplay in the assembly process.
Research fields include translational research, invasion, metastasis, disseminated tumor cells, transcription, tumor-associated proteolysis, targeted therapy, micro-RNA, molecular staging of cancer. Associate Editor of the International Journal of Cancer, and on the Editorial Boards of: Advances in Medical Sciences, Journal of Cellular and Molecular Medicine, Frontiers in Molecular and Cellular Oncology, The Open Surgical Oncology Journal.
Researcher and group leader of the group Differentiation in Cancer, at i3S/Ipatimup and Invited Assistant Professor at the Biology Department of the Faculty of Sciences of the University of Porto.
The Zekiye Altun Professor of Biochemistry and Basic Oncology, Dokuz Eylul University. Member of the Cell Death Research Society of Turkey and Basic Oncology Society.
Computational biology Staff Scientist, Aravind Group, at the Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health (Bethesda, Maryland). Research interest includes studying protein structure, function and sequence, evolution of domains and biological systems to glean information about the biology of organisms.
My laboratory is centered on understanding the function(s) of RNAs, especially non-coding RNAs in all aspects of Biology. The long term objective of our work is to understand meiotic silencing in Neurospora and to map its connections with the meiotic silencing observed in other organisms.
B.S. in Molecular Biology, University of Brasilia, 1982
M.S. in Molecular Biology, University of Brasilia, 1986
Ph.D. in Genetics, University of Georgia (Athens), 1992
Postdoctoral Training, University of Wisconsin Madison, 1993
Postdoctoral Training, Stanford University, 1997
Training: Dentistry, Biomedical Research, Bioengineering, Pathology
Postdoctoral: TGF-beta, wound healing, regeneration, radiation biology, light biology, stem cells, biomaterial, Lasers.
Current: Clinical translational research and molecular mechanism.
Positions: Past-President, NAALT; President-Elect WALT, Co-Chair SPIE, Chair, ASLMS
Interests: Signal Transduction, Lasers, Biological regulation, Photobiomodulation.
Researcher at the Population Genetics and Evolution group at i3S and invited assistant professor at the Faculty of Sciences of the University of Porto. Scientific topics include molecular basis of phenotype-genotype relationships, mechanisms underlying epistatic interactions under the compensatory mutation model, and the dynamics involved in the amino acid substitution at the protein structural level.
Professor of Genetics and Deputy Head of the Department of Genetics, Ecology and Evolution. He is a member of the Brazilian Academy of Sciences and is a Knight of the National Order of Scientific Merit of the Brazilian Ministry of Science, Technology and Innovation. Researcher 1A of the National Council for Scientific and Technological Development (CNPq) which is the highest position.
I am a Professor and Chair, Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Egypt. I am interested in microbiome research, pharmacomicrobiomics, evolution and emergence microbial pathogenesis and resistance, microbial and phage genomics, antibiotic resistance surveillance, adaptive laboratory evolution, metabolic reconstruction and pathway gap filling, and virulence gene discovery.
Jürg Bähler is a Professor of Systems Biology at University College London. His laboratory studies genome regulation during cellular proliferation, quiescence, and ageing using fission yeast (Schizosaccharomyces pombe) as a model system. They apply multiple genetic, computational and genome-wide approaches for systems-level understanding of regulatory processes and complex relationships between genotype, phenotype, and environment, including roles of genome variation and evolution, transcriptome regulation, and non-coding RNAs.
Jürg Bähler is an elected Member of the European Molecular Biology Organisation (EMBO) and a Fellow of the Royal Society of Biology, and he received a Wellcome Trust Senior Investigator Award and a Royal Society Wolfson Research Merit Award.
Kathryn Ball trained as an enzymologist and protein biochemist. She was awarded a Broodbank Fellowship (University of Cambridge) and was the first CRUK Senior Cancer Research Fellow (University of Dundee). She moved to the University of Edinburgh in 2004 where she is the Professor of Biochemistry and Cell Signalling. Her current research is focused on protein structure function analysis and the mechanisms underlying the regulation of protein function by ubiquitin in human health and disease.