Researching the assembly of cell surface appendages in archaea and their role in adhesion and biofilm formation. The model organism we study is the hyperthermophilic archaeon Sulfolobus acidocaldarius. We use genetic approaches to identify systems in Sulfolobus that are involved in the assembly of cell surface appendages and biochemically characterize the subunits and their interplay in the assembly process.
Research fields include translational research, invasion, metastasis, disseminated tumor cells, transcription, tumor-associated proteolysis, targeted therapy, micro-RNA, molecular staging of cancer. Associate Editor of the International Journal of Cancer, and on the Editorial Boards of: Advances in Medical Sciences, Journal of Cellular and Molecular Medicine, Frontiers in Molecular and Cellular Oncology, The Open Surgical Oncology Journal.
Researcher and group leader of the group Differentiation in Cancer, at i3S/Ipatimup and Invited Assistant Professor at the Biology Department of the Faculty of Sciences of the University of Porto.
Dr Patrick Aloy is an ICREA Research Professor and Principal Investigator of the Structural Systems Biology lab at the IRB. He has a BSc in Biochemistry and a MSc in Biotechnology from the Univ. Autònoma de Barcelona, Spain, and spent six years as postdoctoral researcher and staff scientist at the European Molecular Biology Laboratory, Heidelberg, Germany. For fifteen years, Dr Aloy has been developing and implementing new technologies and algorithms, applying state-of-the-art methods to specific problems and bridging the gap between theoretical models and experiments in different disciplines. In the last years, he has pioneered system-scale analyses of macromolecular assemblies and networks using high-resolution three-dimensional structures, which has become a new discipline in structure prediction. Dr Aloy has over 100 publications in first-rate journals, with over 9500 citations and remarkable press coverage, illustrating the scientific and social impact of the work.
The Zekiye Altun Professor of Biochemistry and Basic Oncology, Dokuz Eylul University. Member of the Cell Death Research Society of Turkey and Basic Oncology Society.
Computational biology Staff Scientist, Aravind Group, at the Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health (Bethesda, Maryland). Research interest includes studying protein structure, function and sequence, evolution of domains and biological systems to glean information about the biology of organisms.
I am a Senior Scientist in the Food Nutrition & Health Team at AgResearch, which is one of New Zealand's Crown Research Institutes. I am also an Associate Investigator in the Riddet Centre for Research Excellence based at Massey University. My research focuses on how foods effect the interactions between the host and its resident bacteria, in particular how these alter intestinal barrier function. I have a special interest in the role of the obligate anaerobes, which account for the majority of the bacteria in the intestines but are largely unstudied due to the technical difficulties of co-culturing obligate anaerobes (cannot survive in oxygen) and intestinal cells (require oxygen). Prior to working at AgResearch, I completed my PhD at Massey University investigating the antimicrobial properties of cathelicidin peptides isolated from ovine blood.
Training: Dentistry, Biomedical Research, Bioengineering, Pathology
Postdoctoral: TGF-beta, wound healing, regeneration, radiation biology, light biology, stem cells, biomaterial, Lasers.
Current: Clinical translational research and molecular mechanism.
Positions: Past-President, NAALT; President-Elect WALT, Co-Chair SPIE, Chair, ASLMS
Interests: Signal Transduction, Lasers, Biological regulation, Photobiomodulation.
I am a Professor and Chair, Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Egypt. I am interested in microbiome research, pharmacomicrobiomics, evolution and emergence microbial pathogenesis and resistance, microbial and phage genomics, antibiotic resistance surveillance, adaptive laboratory evolution, metabolic reconstruction and pathway gap filling, and virulence gene discovery.
Jürg Bähler is a Professor of Systems Biology at University College London. His laboratory studies genome regulation during cellular proliferation, quiescence, and ageing using fission yeast (Schizosaccharomyces pombe) as a model system. They apply multiple genetic, computational and genome-wide approaches for systems-level understanding of regulatory processes and complex relationships between genotype, phenotype, and environment, including roles of genome variation and evolution, transcriptome regulation, and non-coding RNAs.
Jürg Bähler is an elected Member of the European Molecular Biology Organisation (EMBO) and a Fellow of the Royal Society of Biology, and he received a Wellcome Trust Senior Investigator Award and a Royal Society Wolfson Research Merit Award.
Kathryn Ball trained as an enzymologist and protein biochemist. She was awarded a Broodbank Fellowship (University of Cambridge) and was the first CRUK Senior Cancer Research Fellow (University of Dundee). She moved to the University of Edinburgh in 2004 where she is the Professor of Biochemistry and Cell Signalling. Her current research is focused on protein structure function analysis and the mechanisms underlying the regulation of protein function by ubiquitin in human health and disease.