Group Leader in Arthritis and Lupus Research Group, Department of Medicine, Monash University. Interests in cytokine biology, inflammasomes, MIF, autophagy, inflammation, innate immunity, veterinary and comparative immunology.
Deputy Editor, Immunology and Cell Biology.
Review Editor, Frontiers in Immunology.
Editorial Board member, Arthritis Research & Therapy.
My research goals are to characterise the mechanisms of collagenous tissue development, repair and renewal. Current research interests include understanding the dynamics of collagen synthesis and turnover, the role of stem cells in musculoskeletal homeostasis and the role of glucose in musculoskeletal ageing. Tissues of interest are primarily tendon and ligament but include cartilage, bone, cornea and intervertebral disc, as well as fibrotic tissue.
This research is important because age-related degeneration and loss of function in musculoskeletal tissues is associated with chronic joint pain, limited movement, tendinopathy, ligament damage, intervertebral disc degeneration and osteoarthritis. There is both a loss of tissue integrity and propensity to fibrosis indicating that homeostasis of the collagenous extracellular matrix is lost with age. Understanding the molecular processes that create functional musculoskeletal tissues during development and growth, and which malfunction or cease to operate in aged tissues is key to developing new strategies for tissue engineering, to activate intrinsic stem cell repair mechanisms and to develop beneficial pharmaceutical, dietary or exercise-based interventions in an increasingly aged society.
Professor of Clinical Neurosciences & Foundation Chair in Physiotherapy, Director of Innovation in Implementation and Clinical Translation (IIMPACT) Research Collaboration at the University of South Australia; Fellow of the Australian Academy of Health & Medical Science; Hon Fellow, Faculty of Pain Medicine, Australia New Zealand College of Anaesthetists; Fellow, Australian College of Physiotherapists & Honoured Member, Australian Physiotherapy Association; Principal Research Fellow, National Health & Medical Research Council of Australia.
Dr. Nguyen is Distinguished Professor of Predictive Medicine at the School of Biomedical Engineering, University of Technology Sydney (Australia). He also holds joint appointments as Professor, St Vincent's Clinical School, University of New South Wales (UNSW Sydney); and adjunct Professor of Epidemiology and Biostatistics at the School of Medicine, University of Notre Dame Australia.
Dr. Pan is a Senior Research Fellow at Menzies Institute for Medical Research. He has been researching both epidemiology and clinical interventions to osteoarthritis-related pain. Much of his work has been on identifying biomechanical risk factors for chronic pain and osteoarthritis, identifying pain and osteoarthritis phenotypes and testing new therapeutic treatments.
Study of Medicine at the Ruprecht-Karls-Universiy in Heidelberg, Germany; Habilitation in Experimental Virology. Head of Clinical Research at the Department of Pediatrics, University Hospital Carl Gustav Carus at TU Dresden, Germany, since 1995. Speaker of Clinical Research Unit 249 "Defects of the Innate Immune System in Autoinflammation and Autoimmunity" since 2010
Anita is an Associate Professor in the School of Public Health and Preventive Medicine, Monash University, and a Clinical Rheumatologist, Alfred Hospital, Melbourne.
Recognised as a world-leader in osteoarthritis research, Anita is based at The Alfred hospital where she combines research with clinical practice as a physician. Her work has contributed to guidelines for managing hip and knee osteoarthritis developed through the Royal Australasian College of General Practitioners National Health and Medical Research Council.