Dr Masahiro Ono was originally trained as a dermatologist, and later specialised in molecular and systems immunology. He obtained his PhD in 2006 on autoimmunity and regulatory T cells, and thereafter, worked on the molecular mechanism of the transcription factor Foxp3, revealing the interaction of Foxp3 and the transcription factor Runx1 and their transcriptional mechanisms. In 2009, he obtained a Human Frontier Science Program Long-Term Fellowship, and joined University College London (UCL). Thus he extended his expertise to genomics and systems analysis, establishing a new multidimensional framework for visualising transcriptomic data and unravelling complex processes in T cell differentiation. In 2012, he was awarded a prestigious Biotechnology and Biological Sciences Research Council (BBSRC) David Phillips Fellowship, thereby established his lab in UCL. In 2015, he was appointed to a proleptic Senior Lecturer in the Department of Life Sciences, Imperial. He is conducting multidisciplinary projects on the transcriptional programme of T cell memory and immune regulation.
MD, U. of Athens, Greece
PhD, Syracuse U, NY
Chief of the Human Retrovirus Section of the National Cancer Institute, USA
Interests: HIV pathogenesis, Molecular Biology, gene regulation, Biotechnology, protein engineering, cytokines, Immunotherapy, Vaccines, Nucleic acid vaccines, gene therapy
Professor of Experimental Neuropathology at the Centre for Biological Sciences of the University of Southampton. Visiting Professor in the College of Medicine and Veterinary Medicine, University of Edinburgh. Fellow of the Academy of Medical Sciences. Chair of the Medical Research Council Neuroscience and Mental Health Board.
Senior Investigator and Chief of the Viral Pathogenesis Section
Laboratory of Viral Diseases, NIAID, NIH
Associate Professor Molecular Cell and Developmental Biology. Presidential Young Investigator (1987).
Researcher at the Institute of Genetics and Biophysics of the National Research Council.
Carlo Pucillo is full professor in Immunology at School of Medicine of University of Udine. In his scientific career Prof. Carlo Pucillo has studied the "non canonical function" of MHC class II and the molecular mechanism that regulate the B cell activation and differentiation. From 2-1991 to 6-1994 Dr Pucillo has been Visiting Scientist at NCI in Bethesda, MD-USA.
He has acquired a considerable expertise in advanced molecular biology analysis as well as a good understanding of the immunobiology of the immune response, of the non canonical function of MHC class II molecules, in particular, as documented by his publications on this subjects.
He has also investigated the signal transduction pathways elicited by T-B cell interaction via CD40-CD154. CD40 is a B cell surface receptor that belongs to the pleiotropic tumor necrosis factor receptor (TNFR) superfamily. The interaction between CD40 and its ligand promotes proliferation, cytokine production, upregulation of various surface molecules involved in antigen presentation, germinal center and memory B cell formation antibody isotype switching and affinity maturation and the B cell life span.
Most recently, his interest is in the study of regulatory role of Mast Cells in the microenvironment and subsequently in the tissutal tolerance and adaptive immune response. This body of work may provide a conceptual framework to therapeutically manipulate these responses in the settings of autoimmune disease and cancer.
Prof. of Nephrology, Director of the Department of Immunology and Clinical Transplantation and Director of the Department of Medicine of the Ospedali Riuniti di Bergamo, Italy. Research Coordinator of the Negri Bergamo Laboratories of the ìMario Negriî Institute for Pharmacological Research. Recipient of ISN Jean Hamburger Award (2005), ASN John. P. Peters Award (2007), ISN AMGEN Award (2011). 2011 appointed as ISN President-elect (2013-2015)
Prof Thomas Ritter, leader of research programme, was recruited by the National University of Ireland, Galway as a lecturer in Gene Therapy and Regenerative Medicine and assumed his position in March 2005. Prof. Ritter has over 20 year experience in the field of gene therapy in organ transplantation. He obtained his Ph.D. degree in 1994 from the Max-Planck Research group of Immunology / Rheumatology at the University of Erlangen-Nuremberg, Germany where he worked on the molecular characterization of T cell receptors specific for human collagen type II. Having completed his Post-Doctoral Fellowship at Marseille, Center of Immunology in 1995, Prof. Ritter took up a faculty position at the prestigious Charité University Hospital in Berlin, Germany. He worked as a leader of the gene therapy programme in experimental transplantation in the Institute of Medical Immunology under the directorship of Prof. Dr. H.-D. Volk. His research focused on the development of efficient viral gene-transfer systems for application in transplantation medicine. Prof. Ritter was successful in obtaining funding from the German Research Foundation and the Ministry of Health and Research as well as from industry (Schering). Prof. Ritter completed his 'Habilitation' (postdoctoral lecture qualification) in Immunology in 2002 followed by a promotion to assistant professor in 2003.
Professor, Dept Plant Pathology and the Genome Center, UC Davis. Director, Grass Genetics, JBEI. Fellow of the American Association for the Advancement of Science. Recipient of the USDA 2008 National Research Initiative Discovery Award. 2009 recipient of the National Association of Science Writers Science in Society Journalism Award. Selected as one of the 100 most creative people in business by Fast Company Magazine. Co-author of Tomorrow's Table: Organic Farming, Genetics, & the Future of Food
Physicist, in 1996 he started his studies in Macromolecular Crystallography at the Advanced Biotechnology Center, Genova (I). In 1997 he achieved the Advanced Certificate in Principles of Protein Structures (PPS). Birkbeck College, University of London, UK. and in 1998 he spent a period at the “York Structural Biology Laboratory”, York University, York, UK for a Macromolecular crystallography traineeship. He participated to the NASA expeditions STS100/ISS6A and STS110/ISS7A, by designing experiment of protein crystallization onboard the International Space Station (ISS). Director of different Courses and Workshops, he is the author/coauthor of more than 100 peer-reviewed scientific publications.
Camillo Rosano has the Habilitation as Full Professor in Biochemistry and Habilitation as Full Professor in Applied Biology. Italian Ministry for University, Education and Research (MIUR), 2012