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Gwyn Gould
Gold Contributor
33,910 Points

Contributions by role

Author 540
Reviewer 70
Editor 33,300

Contributions by subject area

Biochemistry
Cell Biology
Molecular Biology
Cardiology
Diabetes and Endocrinology
Kinesiology
Agricultural Science
Developmental Biology
Plant Science
Bioinformatics
Genetics
Oncology
Drugs and Devices
Nutrition
Pharmacology
Gynecology and Obstetrics
Women's Health
Medical Genetics
Metabolic Sciences
Andrology
Epidemiology
Evidence Based Medicine
Gastroenterology and Hepatology
Microbiology
Virology
HIV
Internal Medicine
Toxicology
Ophthalmology
Computational Biology
Anatomy and Physiology
Global Health
Infectious Diseases
Public Health
Histology
Neuroscience
Immunology
Genomics
Biotechnology
Obesity
Computational Science
Data Science
Entomology
Urology
Nephrology
Geriatrics
Otorhinolaryngology
Psychiatry and Psychology
Data Mining and Machine Learning
Biophysics
Radiology and Medical Imaging
Orthopedics
Rheumatology
Translational Medicine
Dentistry
Health Policy
Statistics
Pathology
Allergy and Clinical Immunology
Respiratory Medicine
Zoology
Anesthesiology and Pain Management
Hematology
Neurology
Pediatrics
Sports Medicine
Animal Behavior
Science and Medical Education
Science Policy
COVID-19
Emergency and Critical Care
Surgery and Surgical Specialties
Aquaculture, Fisheries and Fish Science
Food Science and Technology
Mycology
Bioengineering
Dermatology
Cognitive Disorders
Veterinary Medicine
Clinical Trials
Freshwater Biology
Healthcare Services
Spatial and Geographic Information Science
Gold Contributor

Gwyn W Gould

PeerJ Editor, Author & Reviewer

Summary

Gwyn is Professor in the Strathclyde Institute of Pharmacy and Biomedical Sciences at the University of Strathclyde where he has recently moved his lab. He did his undergraduate and postgraduate work at the University of Southampton, studying lipid/protein interactions under the supervision of Tony Lee for his PhD. This was followed by postdoctoral work at Dartmouth Medical School where his interest in membrane trafficking began. After a 30-year career at the University of Glasgow, he has moved to the Strathclyde Institute of Pharmacy and Biomedical Sciences where his research continues to focus upon the control of glucose transport by insulin in adipocytes, muscle and cardiac tissue.

Biochemistry Cell Biology Diabetes & Endocrinology

Section Editor

Biochemistry, Biophysics and Molecular Biology

Editorial Board Member

PeerJ - the Journal of Life & Environmental Sciences

Past or current institution affiliations

University of Strathclyde

Work details

Professor

University of Strathclyde
October 2019
Strathclyde Institute of Pharmacy and Biomedical Sciences

Websites

  • LinkedIn
  • Gould Lab website
  • Twitter

PeerJ Contributions

  • Articles 4
  • Edited 160
July 24, 2023
Phosphorylation of the N-terminus of Syntaxin-16 controls interaction with mVps45 and GLUT4 trafficking in adipocytes
Shaun K. Bremner, Rebecca Berends, Alexandra Kaupisch, Jennifer Roccisana, Calum Sutherland, Nia J. Bryant, Gwyn W. Gould
https://doi.org/10.7717/peerj.15630 PubMed 37520260
January 5, 2023
A systematic analysis of anti-diabetic medicinal plants from cells to clinical trials
Simeon Omale, Kennedy I. Amagon, Titilayo O. Johnson, Shaun Kennedy Bremner, Gwyn W. Gould
https://doi.org/10.7717/peerj.14639 PubMed 36627919
May 25, 2021
Run for your life: can exercise be used to effectively target GLUT4 in diabetic cardiac disease?
Peter R.T. Bowman, Godfrey L. Smith, Gwyn W. Gould
https://doi.org/10.7717/peerj.11485 PubMed 34113491
March 5, 2020
Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes
Silke Morris, Niall D. Geoghegan, Jessica B.A. Sadler, Anna M. Koester, Hannah L. Black, Marco Laub, Lucy Miller, Linda Heffernan, Jeremy C. Simpson, Cynthia C. Mastick, Jon Cooper, Nikolaj Gadegaard, Nia J. Bryant, Gwyn W. Gould
https://doi.org/10.7717/peerj.8751 PubMed 32185116

Academic Editor on

July 9, 2025
Effect of modulating the extracellular matrix cross linkage by genipin on tumor cell resistance and survival in thioacetamide-induced hepatocellular carcinoma in rats
Hanan M. Hassan, Mohammed Baradwan, Alaa Bagalagel, Reem Diri, Ahmed Basilim, Mohammed Z. Nasrullah, Abdulhamid Althagafi, Hussam I. Kutbi, Abdulaziz A. Mohammed, Hanan M. Alshan, Mohammed M.H. Al-Gayyar
https://doi.org/10.7717/peerj.19680 PubMed 40656954
May 29, 2025
Role of hypothalamus function in metabolic diseases and its potential mechanisms
Xinyu Zhang, Jie Yang, Yilin Li, Yulin Li, Guoqi Li
https://doi.org/10.7717/peerj.19532 PubMed 40452923
May 26, 2025
A genetically engineered mouse model for ovarian hyperstimulation syndrome
Wenkai Bi, Xinchen Jin, Shanshan Wu, Jing Wang, Xinhuan Su, Ling Gao, Zhao He
https://doi.org/10.7717/peerj.19531 PubMed 40444288
March 28, 2025
The role of endoplasmic reticulum stress in type 2 diabetes mellitus mechanisms and impact on islet function
Zhaxicao He, Qian Liu, Yan Wang, Bing Zhao, Lumei Zhang, Xia Yang, Zhigang Wang
https://doi.org/10.7717/peerj.19192 PubMed 40166045
March 27, 2025
Assessment of liquid media requirements for storing and evaluating respiratory cilia motility
Richard Francis
https://doi.org/10.7717/peerj.19191 PubMed 40161338
March 24, 2025
Polyunsaturated fatty acids and their endocannabinoid-related metabolites activity at human TRPV1 and TRPA1 ion channels expressed in HEK-293 cells
Atnaf Abate, Marina Santiago, Alfonso Garcia-Bennett, Mark Connor
https://doi.org/10.7717/peerj.19125 PubMed 40151457
March 12, 2025
Extracellular vesicles in endometrial-related diseases: role, potential and challenges
Zilu Wang, Feng Li, Wenqiong Liu
https://doi.org/10.7717/peerj.19041 PubMed 40093416
March 3, 2025
Effect of high glucose on the gene expression profiling in cardiac fibroblasts from rats at different ages
Quqian Mo, Angyu Zhan, Ruining Bai, Shaoling Lin, Jiaojiao Feng, Tongjun Li, Zijian Lao, Xiao Yang, Keke Wang, Xianglu Rong, Lexun Wang
https://doi.org/10.7717/peerj.19040
February 17, 2025
A retrospective study of the correlation between high serum ferritin levels and the risk of gestational diabetes mellitus in midpregnant women
Xizhenzi Fan, Pan Zhang, Lingli Wang, Wenhui Song, Achou Su, Tianxiao Yu
https://doi.org/10.7717/peerj.18965 PubMed 39981048
February 13, 2025
Activation of autophagy is required for clearance of mitochondrial ROS in patients with asthenozoospermia
Xiaona Wang, Shiyuan Huang, Yu Zhao, Hua Chen, Linzhi Yan, Hongshan Ge, Xinmei Wu
https://doi.org/10.7717/peerj.18827 PubMed 39959826
January 16, 2025
Predictors of county-level diabetes-related mortality risks in Florida, USA: a retrospective ecological study
Nirmalendu Deb Nath, Agricola Odoi
https://doi.org/10.7717/peerj.18537 PubMed 39830967
January 3, 2025
The effect of the Wnt pathway on the osteogenic differentiation of periodontal ligament stem cells in different environments
Qi Su, Fengqiong Huang, XiuLei Fang, Qiang Lin
https://doi.org/10.7717/peerj.18770 PubMed 39763707
November 15, 2024
miR-101-3p suppresses proliferation of orbital fibroblasts by targeting pentraxin-3 in thyroid eye disease
Yanfei Zhu, Yuqing Chen, Xingyi Shu, Ruili Wei
https://doi.org/10.7717/peerj.18535 PubMed 39559327
October 24, 2024
Effect of acute anaerobic performance on zinc alpha 2 glycoprotein, apelin and lipasin levels
Şaban Ünver, İlknur Bıyık, Tülin Akman, Emre Şimşek, Hamza Küçük, Abdurrahim Kaplan, Deniz Günay Derebaşı, Selma İşler, Canberk Çınar, Tuba Kızılet, Yeliz Tanrıverdi Çaycı
https://doi.org/10.7717/peerj.18093 PubMed 39465147
October 8, 2024
The vaginal metabolomics profile with features of polycystic ovary syndrome: a pilot investigation in China
Yan Xuan, Xiang Hong, Xu Zhou, Tao Yan, Pengfei Qin, Danhong Peng, Bei Wang
https://doi.org/10.7717/peerj.18194 PubMed 39399434
August 30, 2024
miR-605-3p may affect caerulein-induced ductal cell injury and pyroptosis in acute pancreatitis by targeting the DUOX2/NLRP3/NF-κB pathway
Gai Zhang, Yuanyuan Zhang, Bing Wang, Hao Xu, Donghui Xie, Zhenli Guo
https://doi.org/10.7717/peerj.17874 PubMed 39224819
August 29, 2024
Beyond 2D cell cultures: how 3D models are changing the in vitro study of ovarian cancer and how to make the most of them
Marilisa Cortesi, Kristina Warton, Caroline E. Ford
https://doi.org/10.7717/peerj.17603 PubMed 39221267
August 14, 2024
PCSK9 inhibitor effectively alleviated cognitive dysfunction in a type 2 diabetes mellitus rat model
Yang Yang, Yeying Wang, Yuwen Wang, Tingyu Ke, Ling Zhao
https://doi.org/10.7717/peerj.17676 PubMed 39157774
August 12, 2024
The role of protein post-translational modifications in prostate cancer
Yinghui Hao, Chenqiong Gu, Wenfeng Luo, Jian Shen, Fangmei Xie, Ying Zhao, Xiaoyu Song, Zeping Han, Jinhua He
https://doi.org/10.7717/peerj.17768 PubMed 39148683
July 30, 2024
Transcription factor NF-E2-related factor 2 plays a critical role in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) by regulating ferroptosis
JiaLi Deng, Na Li, Liyuan Hao, Shenghao Li, Nie Aiyu, Junli Zhang, XiaoYu Hu
https://doi.org/10.7717/peerj.17692 PubMed 39670103
July 24, 2024
Evaluation of in-house dengue real-time PCR assays in West Java, Indonesia
Denti R. Kinanti, Intan Ahmad, Ramadhani Putra, Sri Yusmalinar, Indra Wibowo, Tjandra Anggraeni, Angga Dwiartama, Tommy Octavianus Soetrisno Tjia, Putri Cahya Destiani, Karimatu Khoirunnisa, Wu-Chun Tu, Kok-Boon Neoh, Rosye Arosdiani Apip, Ahyani Raksanagara, Ira Dewi Jani, Yeppi Tisnawati, Aan Warisman, Tita Rostiana, Azzania Fibriani
https://doi.org/10.7717/peerj.17758 PubMed 39071132
May 30, 2024
Crizotinib inhibits the metabolism of tramadol by non-competitive suppressing the activities of CYP2D1 and CYP3A2
Nanyong Gao, Xiaoyu Xu, Feng Ye, Xin-yue Li, Chengqi Lin, Xiu-wei Shen, Jianchang Qian
https://doi.org/10.7717/peerj.17446 PubMed 38827306
May 21, 2024
Pseudotargeted lipidomics analysis of scoparone on glycerophospholipid metabolism in non-alcoholic steatohepatitis mice by LC-MRM-MS
Qi Song, Ziyi Zhao, Hu Liu, Jinling Zhang, Zhiqiang Wang, Yunqi Zhang, Guowei Ma, Shaoqin Ge
https://doi.org/10.7717/peerj.17380 PubMed 38799063
May 3, 2024
A comparison of five methods to maximize RNA and DNA isolation yield from adipose tissue
Pawel Dabrowski, Marta Rasmus, Arkadiusz Jundzill, Tomasz Drewa, Marta Pokrywczynska
https://doi.org/10.7717/peerj.17071 PubMed 38711623
March 25, 2024
Identification and validation of an endoplasmic-reticulum-stress-related gene signature as an effective diagnostic marker of endometriosis
Tao Wang, Mei Ji, Jing Sun
https://doi.org/10.7717/peerj.17070 PubMed 38549776
January 25, 2024
Gpr149 is involved in energy homeostasis in the male mouse
Steven Wyler, Surbhi, Newton Cao, Warda Merchant, Angie Bookout, Laurent Gautron
https://doi.org/10.7717/peerj.16739 PubMed 38282864
January 16, 2024
Reversal of cholestatic liver disease by the inhibition of sphingosine 1-phosphate receptor 2 signaling
Huiling Cao, Lin Chen, Ziyang Zeng, Xianfeng Wu, Yuhao Lei, Wen Jia, Guang Yue, Bin Yi, Yu-jie Li, Yuan Shi
https://doi.org/10.7717/peerj.16744 PubMed 38250717
November 20, 2023
Insight from the association between critical thinking and English argumentative writing: catering to English learners’ writing ability
Yanfang Hu, Atif Saleem
https://doi.org/10.7717/peerj.16435 PubMed 38025684
October 31, 2023
Small extracellular vesicles derived from umbilical cord mesenchymal stem cells repair blood-spinal cord barrier disruption after spinal cord injury through down-regulation of Endothelin-1 in rats
Chenhui Xue, Xun Ma, Xiaoming Guan, Haoyu Feng, Mingkui Zheng, Xihua Yang
https://doi.org/10.7717/peerj.16311 PubMed 37927780
October 19, 2023
Tissue-specific expression of senescence biomarkers in spontaneously hypertensive rats: evidence of premature aging in hypertension
Ratthapon Somsura, Kanokwan Kamkajon, Khuanjit Chaimongkolnukul, Surachai Chantip, Jarinthorn Teerapornpuntakit, Kannikar Wongdee, Nuntaporn Kamonsutthipaijit, Suwimol Tangtrongsup, Nattapon Panupinthu, Wacharaporn Tiyasatkulkovit, Narattaphol Charoenphandhu
https://doi.org/10.7717/peerj.16300 PubMed 37872946
October 16, 2023
Long non‑coding RNA L13Rik promotes high glucose-induced mesangial cell hypertrophy and matrix protein expression by regulating miR-2861/CDKN1B axis
Linlin Sun, Miao Ding, Fuhua Chen, Dingyu Zhu, Xinmiao Xie
https://doi.org/10.7717/peerj.16170 PubMed 37868060
October 9, 2023
Distribution of multidrug-resistant bacterial infections in diabetic foot ulcers and risk factors for drug resistance: a retrospective analysis
Huihui Guo, Qiwei Song, Siwei Mei, Zhenqiang Xue, Junjie Li, Tao Ning
https://doi.org/10.7717/peerj.16162 PubMed 37842066
September 1, 2023
Construction and validation of a PANoptosis-related lncRNA signature for predicting prognosis and targeted drug response in thyroid cancer
Ruowen Li, Mingjian Zhao, Min Sun, Chengxu Miao, Jinghui Lu
https://doi.org/10.7717/peerj.15884 PubMed 37671354
August 30, 2023
Intestinal GPDH-1 regulates high glucose diet induced lifespan extension in aged worms
Jihao Mo, Zhenzhen Zhang, Xiaowei Wang, Miaomiao Wang, Ning Sun, Lei Wang, Meimei Wang
https://doi.org/10.7717/peerj.15845 PubMed 37663291
August 3, 2023
GGA1 participates in spermatogenesis in mice under stress
Haoyun Jiao, Yinghong Chen, Tingting Han, Qiyu Pan, Fei Gao, Guoping Li
https://doi.org/10.7717/peerj.15673 PubMed 37551344
July 19, 2023
In silico identification and in vitro assessment of a potential anti-breast cancer activity of antimicrobial peptide retrieved from the ATMP1 Anabas testudineus fish peptide
Douglas Law, Ahmed Abdulkareem Najm, Jia Xuan Chong, Joelene Zi Ying K’ng, Mas Amran, Huey Lih Ching, Rui Rui Wong, May Ho Leong, Ibrahim Mahmood Mahdi, Shazrul Fazry
https://doi.org/10.7717/peerj.15651 PubMed 37483971
July 19, 2023
mRNA sequencing reveals the distinct gene expression and biological functions in cardiac fibroblasts regulated by recombinant fibroblast growth factor 2
Changye Sun, Mengru Bai, Yangyang Jia, Xiangqin Tian, Yonglong Guo, Xinhui Xu, Zhikun Guo
https://doi.org/10.7717/peerj.15736 PubMed 37483983
July 3, 2023
Measuring blood glucose before or after lumbar puncture
Kaili Shi, Xue Li, Ying Li, Xiaohua Tan, Kelu Zheng, Wenxiong Chen, Xiaojing Li
https://doi.org/10.7717/peerj.15544 PubMed 37426413
June 30, 2023
miR-455-3p ameliorates pancreatic acinar cell injury by targeting Slc2a1
Yinchu Zhan, Chenlin Chen, Zhiqiang Wu, Feng Zhou, Xinping Yu
https://doi.org/10.7717/peerj.15612 PubMed 37404474
June 29, 2023
TMEM200A is a potential prognostic biomarker and correlated with immune infiltrates in gastric cancer
Fujin Fang, Tiantian Zhang, Huan Lei, Xiaobing Shen
https://doi.org/10.7717/peerj.15613 PubMed 37404478
June 27, 2023
Construction and validation of a novel IGFBP3-related signature to predict prognosis and therapeutic decision making for Hepatocellular Carcinoma
Jianlin Chen, Wanzhen Zhuang, Yu Xia, Xiaoqing Yin, Mingshu Tu, Yi Zhang, Liangming Zhang, Hengbin Huang, Songgao Zhang, Lisheng You, Yi Huang
https://doi.org/10.7717/peerj.15554 PubMed 37397026
June 23, 2023
Luteolin supplementation during porcine oocyte maturation improves the developmental competence of parthenogenetic activation and cloned embryos
Pil-Soo Jeong, Hae-Jun Yang, Se-Been Jeon, Min-Ah Gwon, Min Ju Kim, Hyo-Gu Kang, Sanghoon Lee, Young-Ho Park, Bong-Seok Song, Sun-Uk Kim, Deog-Bon Koo, Bo-Woong Sim
https://doi.org/10.7717/peerj.15618 PubMed 37377789
June 7, 2023
Diagnostic value and characteristic analysis of serum nucleocapsid antigen in COVID-19 patients
Xihong Zhang, Chungen Qian, Li Yang, Huixia Gao, Ping Jiang, Muwei Dai, Yuling Wang, Haiyan Kang, Yi Xu, Qian Hu, Fumin Feng, Bangning Cheng, Erhei Dai
https://doi.org/10.7717/peerj.15515 PubMed 37304882
June 5, 2023
AMHconverter: an online tool for converting results between the different anti-Müllerian hormone assays of Roche Elecsys®, Beckman Access, and Kangrun
Huiyu Xu, Guoshuang Feng, Congcong Ma, Yong Han, Jiansuo Zhou, Jiatian Song, Yuan Su, Qun Zhong, Fenghua Chen, Liyan Cui, Rong Li
https://doi.org/10.7717/peerj.15301 PubMed 37304879
May 29, 2023
Assessment of eight insulin resistance surrogate indexes for predicting metabolic syndrome and hypertension in Thai law enforcement officers
Rujikorn Rattanatham, Jitbanjong Tangpong, Moragot Chatatikun, Dali Sun, Fumitaka Kawakami, Motoki Imai, Wiyada Kwanhian Klangbud
https://doi.org/10.7717/peerj.15463 PubMed 37273533
May 17, 2023
Association of lipid accumulation product and visceral adiposity index with the risk of hypertension among oil workers in Xinjiang, China
Guliman Muheiyati, Yujie Mei, Ning Tao
https://doi.org/10.7717/peerj.15273 PubMed 37214102
May 11, 2023
m6A eraser ALKBH5 mitigates the apoptosis of cardiomyocytes in ischemia reperfusion injury through m6A/SIRT1 axis
Liangliang Liu, Zhen Liu
https://doi.org/10.7717/peerj.15269 PubMed 37193033
April 24, 2023
Association of ApoE gene polymorphisms with serum lipid levels and the risk of type 2 diabetes mellitus in the Chinese Han population of central China
Yali Zeng, Shuang Wen, Lijun Huan, Liang Xiong, Botao Zhong, Pengyun Wang
https://doi.org/10.7717/peerj.15226 PubMed 37123009
April 17, 2023
The effects of chronic unpredicted mild stress on maternal negative emotions and gut microbiota and metabolites in pregnant rats
Rui Wang, Feng Zhao, Ye Li, Jiashu Zhu, Yifei Liu, Jiaqi Li, Guixiang Yao, Hongya Liu, Suzhen Guan, Shuqin Ma
https://doi.org/10.7717/peerj.15113 PubMed 37090110
April 13, 2023
Alterations of the gut microbiota in type 2 diabetics with or without subclinical hypothyroidism
Yanrong Lv, Rong Liu, Huaijie Jia, Xiaolan Sun, Yuhan Gong, Li Ma, Wei Qiu, Xiaoxia Wang
https://doi.org/10.7717/peerj.15193 PubMed 37073275
March 31, 2023
miR-126 promotes M1 to M2 macrophage phenotype switching via VEGFA and KLF4
Xinyang Shou, Yimin Wang, Qingyu Jiang, Jun Chen, Qiang Liu
https://doi.org/10.7717/peerj.15180 PubMed 37020848
March 27, 2023
m6A reader IGF2BP1 accelerates apoptosis of high glucose-induced vascular endothelial cells in a m6A-HMGB1 dependent manner
Anru Liang, Jianyu Liu, Yanlin Wei, Yuan Liao, Fangxiao Wu, Jiang Ruan, Junjun Li
https://doi.org/10.7717/peerj.14954 PubMed 37009154
March 20, 2023
Development of a new generation of miniemulsion based on cottonseed oil with α-tocopherol and ZnO and evaluation of its adjuvant activity
Gustavo Sobrevilla-Hernández, Moisés Armides Franco-Molina, Diana G. Zárate-Triviño, Jorge R. Kawas, Sara Paola Hernández-Martínez, Paola Leonor García-Coronado, Silvia Elena Santana-Krímskaya, Cynthia Aracely Alvizo-Báez, Cristina Rodríguez-Padilla
https://doi.org/10.7717/peerj.14981 PubMed 36968001
March 20, 2023
GOLPH3 modulates expression and alternative splicing of transcription factors associated with endometrial decidualization in human endometrial stromal cells
Suqin Zhu, Dianliang Lin, Zhoujie Ye, Xiaojing Chen, Wenwen Jiang, Huiling Xu, Song Quan, Beihong Zheng
https://doi.org/10.7717/peerj.15048 PubMed 36967990
March 13, 2023
Dihydrotanshinone I inhibits hepatocellular carcinoma cells proliferation through DNA damage and EGFR pathway
Linjun Wang, Xiangwei Xu, Dexing Chen, Chenghang Li
https://doi.org/10.7717/peerj.15022 PubMed 36935927
March 10, 2023
Anti-leukemic effect of menthol, a peppermint compound, on induction of apoptosis and autophagy
Mashima Naksawat, Chosita Norkaew, Kantorn Charoensedtasin, Sittiruk Roytrakul, Dalina Tanyong
https://doi.org/10.7717/peerj.15049 PubMed 36923503
February 9, 2023
Bioinformatics prediction and experimental verification of a novel microRNA for myocardial fibrosis after myocardial infarction in rats
Qianqian Guo, Dandan Wu, Dongdong Jia, Xinyue Zhang, Aiming Wu, Lixia Lou, Mingjing Zhao, Mengzhu Zhao, Yijie Gao, Manman Wang, Menghua Liu, Meng Chen, Dongmei Zhang
https://doi.org/10.7717/peerj.14851 PubMed 36788811
February 8, 2023
A novel gene signature related to oxidative stress predicts the prognosis in clear cell renal cell carcinoma
Sheng Ma, Yue Ge, Zezhong Xiong, Yanan Wang, Le Li, Zheng Chao, Beining Li, Junbiao Zhang, Siquan Ma, Jun Xiao, Bo Liu, Zhihua Wang
https://doi.org/10.7717/peerj.14784 PubMed 36785707
February 6, 2023
Construction and validation of a fatty acid metabolism-related gene signature for predicting prognosis and therapeutic response in patients with prostate cancer
Hongjun Zhao, Tong Wu, Zehao Luo, Qinyao Huang, Sihua Zhu, Chunling Li, Zubing Zhang, Jiahao Zhang, Jianwen Zeng, Yuying Zhang
https://doi.org/10.7717/peerj.14854 PubMed 36778142
January 31, 2023
Bidirectional effect of vitamin D on brown adipogenesis of C3H10T1/2 fibroblast-like cells
Takako Mukai, Tatsuya Kusudo
https://doi.org/10.7717/peerj.14785 PubMed 36815991
January 25, 2023
Combination of Vitamin C and Lenvatinib potentiates antitumor effects in hepatocellular carcinoma cells in vitro
Xinyue Wang, Songyi Qian, Siyi Wang, Sheng Jia, Nishang Zheng, Qing Yao, Jian Gao
https://doi.org/10.7717/peerj.14610 PubMed 36718449
January 24, 2023
Mesenchymal stem cell-derived extracellular vesicles, osteoimmunology and orthopedic diseases
Maoxiao Ma, Guofeng Cui, Youwen Liu, Yanfeng Tang, Xiaoshuai Lu, Chen Yue, Xue Zhang
https://doi.org/10.7717/peerj.14677 PubMed 36710868
January 17, 2023
Low temperature upregulating HSP70 expression to mitigate the paclitaxel-induced damages in NHEK cell
Liang Chen, Yi Xu
https://doi.org/10.7717/peerj.14630 PubMed 36684674
January 16, 2023
Transcription analyses of differentially expressed mRNAs, lncRNAs, circRNAs, and miRNAs in the growth plate of rats with glucocorticoid-induced growth retardation
Mingyue Yin, Junqi Wang, Juanjuan Zhang, Wei Wang, Wenli Lu, Fei Xu, Xiaoyu Ma, Sheng Lyu, Lifen Chen, Lidan Zhang, Zhiya Dong, Yuan Xiao
https://doi.org/10.7717/peerj.14603 PubMed 36684670
January 10, 2023
UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion
Yunfeng Tang, Lixin Sun, Yun Zhao, Jingchun Yao, Zhong Feng, Zhong Liu, Guimin Zhang, Chenghong Sun
https://doi.org/10.7717/peerj.14483 PubMed 36643627
January 10, 2023
Comprehensive analysis of fatty acid metabolism-related gene signatures for predicting prognosis in patients with prostate cancer
Hongbo Wang, Zhendong Liu, Yubo Wang, Dali Han, Yuelin Du, Bin Zhang, Yang He, Junyao Liu, Wei Xiong, Xingxing Zhang, Yanzheng Gao, Panfeng Shang
https://doi.org/10.7717/peerj.14646 PubMed 36643625
January 9, 2023
Exosomes derived from M1 macrophages inhibit the proliferation of the A549 and H1299 lung cancer cell lines via the miRNA-let-7b-5p-GNG5 axis
Jingcui Peng, Sa Li, Bin Li, WenXia Hu, Cuimin Ding
https://doi.org/10.7717/peerj.14608 PubMed 36643646
January 9, 2023
The relationship of low-density lipoprotein cholesterol and all-cause or cardiovascular mortality in patients with type 2 diabetes: a retrospective study
Chin-Huan Chang, Shu-Tin Yeh, Seng-Wei Ooi, Chung-Yi Li, Hua-Fen Chen
https://doi.org/10.7717/peerj.14609 PubMed 36643628
December 12, 2022
Association between type 2 diabetes and 5-year overall survival in early-stage pancreatic cancer: a retrospective cohort study
Zhiyin Tang, Wanfeng Xu, Mingming Zhang
https://doi.org/10.7717/peerj.14538 PubMed 36530401
November 1, 2022
PIN1 protects auditory hair cells from senescence via autophagy
Zhe Lv, Yanzhuo Zhang, Huan Cao, Qingjuan Liu, Xiaojuan Feng, Huan Yin, BaoShan Wang
https://doi.org/10.7717/peerj.14267 PubMed 36340199
October 26, 2022
Five-year LDL-cholesterol trend and its predictors among type 2 diabetes patients in an upper-middle-income country: a retrospective open cohort study
Kim Sui Wan, Noran Naqiah Hairi, Feisul Mustapha, Mastura Ismail, Muhammad Fadhli Mohd Yusoff, Foong Ming Moy
https://doi.org/10.7717/peerj.13816 PubMed 36317122
October 26, 2022
De novo transcriptome assembly using Illumina sequencing and development of EST-SSR markers in a monoecious herb Sagittaria trifolia Linn
Hanqing Tang, Josphat K. Saina, Zhi-Cheng Long, Jinming Chen, Can Dai
https://doi.org/10.7717/peerj.14268 PubMed 36317118
October 25, 2022
Icariside II induces rapid phosphorylation of endothelial nitric oxide synthase via multiple signaling pathways
Wenpeng Song, Yiming Yuan, Xiaohui Tan, Yangyang Gu, Jianyu Zeng, Weidong Song, Zhongcheng Xin, Dong Fang, Ruili Guan
https://doi.org/10.7717/peerj.14192 PubMed 36312762
October 10, 2022
Rapid and convenient detection of SARS-CoV-2 using a colorimetric triple-target reverse transcription loop-mediated isothermal amplification method
Zhu Yang, Nicole Y. Liu, Zhiwei Zhu, Minmin Xiao, Shuzhi Zhong, Qiqi Xue, Lina Nie, Jinhong Zhao
https://doi.org/10.7717/peerj.14121 PubMed 36248705
October 10, 2022
PLA2R-IgG4 antibody as a predictive biomarker of treatment effectiveness and prognostic evaluation in patients with idiopathic membranous nephropathy: a retrospective study
Yiqing Huang, Junyi Zhou, Kezhi Zhou, Biao Huang, Jing Xue, Xiran Zhang, Bin Liu, Zhijian Zhang, Leting Zhou, Ting Cai, Yi Zhang, Zhigang Hu, Liang Wang, Xiaobin Liu
https://doi.org/10.7717/peerj.14193 PubMed 36248712
October 4, 2022
Effects of combination of obesity, diabetes, and hypoxia on inflammatory regulating genes and cytokines in rat pancreatic tissues and serum
Sarah Albogami, Aziza Hassan, Sekena H. Abdel-Aziem, Saqer Alotaibi, Fayez Althobaiti, Ahmed El-Shehawi, Alaa Alnefaie, Reem Abdulla Alhamed
https://doi.org/10.7717/peerj.13990 PubMed 36213511
August 29, 2022
TRIM38 protects H9c2 cells from hypoxia/reoxygenation injury via the TRAF6/TAK1/NF-κB signalling pathway
Zhengri Lu, Mengen Deng, Genshan Ma, Lijuan Chen
https://doi.org/10.7717/peerj.13815 PubMed 36061751
August 23, 2022
The effects of university students’ fragmented reading on cognitive development in the new media age: evidence from Chinese higher education
Wei Liu, Heng Huang, Atif Saleem, Zhongping Zhao
https://doi.org/10.7717/peerj.13861 PubMed 36032958
August 15, 2022
The role of autophagy in high-fat diet-induced insulin resistance of adipose tissues in mice
Yovita Permata Budi, Yi-Hsuan Li, Chien Huang, Mu-En Wang, Yi-Chun Lin, De-Shien Jong, Chih-Hsien Chiu, Yi-Fan Jiang
https://doi.org/10.7717/peerj.13867 PubMed 35990905
August 15, 2022
Flotillin-1 promotes EMT of gastric cancer via stabilizing Snail
Ying Huang, Yun Guo, Yi Xu, Fei Liu, Suli Dai
https://doi.org/10.7717/peerj.13901 PubMed 35990908
August 12, 2022
Integrase deficient lentiviral vector: prospects for safe clinical applications
Chee-Hong Takahiro Yew, Narmatha Gurumoorthy, Fazlina Nordin, Gee Jun Tye, Wan Safwani Wan Kamarul Zaman, Jun Jie Tan, Min Hwei Ng
https://doi.org/10.7717/peerj.13704 PubMed 35979475
August 4, 2022
HMGB1-activatied NLRP3 inflammasome induces thrombocytopenia in heatstroke rat
Huimei Yin, Ming Wu, Yong Lu, Xinghui Wu, BaoJun Yu, Ronglin Chen, JieFu Lu, Huasheng Tong
https://doi.org/10.7717/peerj.13799 PubMed 35945940
July 29, 2022
Screening of ferroptosis-related genes in sepsis-induced liver failure and analysis of immune correlation
Qingli Chen, Luxiang Liu, Shuangling Ni
https://doi.org/10.7717/peerj.13757 PubMed 35923893
July 27, 2022
Quality of care and prescription patterns among patients with diabetic kidney disease—a large-scale cohort study from Taiwanese clinics
Kun-Yuan Tsai, Samuel Chen, Chien-Wen Chou, Thing-Fong Tzeng, Yau-Jiunn Lee, Min-ling Chen
https://doi.org/10.7717/peerj.13636 PubMed 35915752
July 19, 2022
Ubiquitin-proteasome system in diabetic retinopathy
Zane Svikle, Beate Peterfelde, Nikolajs Sjakste, Kristine Baumane, Rasa Verkauskiene, Chi-Juei Jeng, Jelizaveta Sokolovska
https://doi.org/10.7717/peerj.13715 PubMed 35873915
July 12, 2022
Downregulation of the enhancer of zeste homolog 1 transcriptional factor predicts poor prognosis of triple-negative breast cancer patients
Wei Peng, Wei Tang, Jian-Di Li, Rong-Quan He, Jia-Yuan Luo, Zu-Xuan Chen, Jiang-Hui Zeng, Xiao-Hua Hu, Jin-Cai Zhong, Yang Li, Fu-Chao Ma, Tian-Yi Xie, Su-Ning Huang, Lian-Ying Ge
https://doi.org/10.7717/peerj.13708 PubMed 35846880
July 8, 2022
Optimizing human coronavirus OC43 growth and titration
Christopher Savoie, Roger Lippé
https://doi.org/10.7717/peerj.13721 PubMed 35833016
June 28, 2022
G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice
Damin Yun, Liwei Zhou, Jie Shi, Xinyao Li, Xiaolong Wu, Fei Sun
https://doi.org/10.7717/peerj.13532 PubMed 35782098
June 23, 2022
Inflammation and fibrosis in the coal dust-exposed lung described by confocal Raman spectroscopy
Wenyang Wang, Min Mu, Yuanjie Zou, Bing Li, Hangbing Cao, Dong Hu, Xinrong Tao
https://doi.org/10.7717/peerj.13632 PubMed 35765591
June 14, 2022
AntiDMPpred: a web service for identifying anti-diabetic peptides
Xue Chen, Jian Huang, Bifang He
https://doi.org/10.7717/peerj.13581 PubMed 35722269
June 10, 2022
Organ-specific expression of genes involved in iron homeostasis in wheat mutant lines with increased grain iron and zinc content
Saule Kenzhebayeva, Saule Atabayeva, Fatma Sarsu, Alfiya Abekova, Sabina Shoinbekova, Nargul Omirbekova, Gulina Doktyrbay, Aizhan Beisenova, Yuri Shavrukov
https://doi.org/10.7717/peerj.13515 PubMed 35707120
June 6, 2022
Cell division cycle associated 2 (CDCA2) upregulation promotes the progression of hepatocellular carcinoma in a p53-dependant manner
Jiahui Wang, Xin Liu, Hongjin Chu, Jian Chen
https://doi.org/10.7717/peerj.13535 PubMed 35694386
June 2, 2022
Calotropin and corotoxigenin 3-O-glucopyranoside from the desert milkweed Asclepias subulata inhibit the Na+/K+-ATPase activity
Salvador E. Meneses-Sagrero, Luisa A. Rascón-Valenzuela, Juan C. García-Ramos, Wagner Vilegas, Aldo A. Arvizu-Flores, Rogerio R. Sotelo-Mundo, Ramon E. Robles-Zepeda
https://doi.org/10.7717/peerj.13524 PubMed 35673388
May 24, 2022
Down-regulated NEDD4L facilitates tumor progression through activating Notch signaling in lung adenocarcinoma
Liping Lin, Xuan Wu, Yuanxue Jiang, Caijiu Deng, Xi Luo, Jianjun Han, Jiazhu Hu, Xiaolong Cao
https://doi.org/10.7717/peerj.13402 PubMed 35646490
May 24, 2022
E161111 is an ultra-short-acting etomidate analogue with stable haemodynamics that elicits only slight adrenocortical suppression in rats
Bin Wang, Deying Gong, Yi Kang, Jin Liu, Jun Yang, Wen-sheng Zhang
https://doi.org/10.7717/peerj.13492 PubMed 35646481
May 10, 2022
An open source and convenient method for the wide-spread testing of COVID-19 using deep throat sputum samples
Sunny C. Huang, Thomas K. Pak, Cameron P. Graber, Charles C. Searby, Guanghao Liu, Jennifer Marcy, Alexandra K. Yaszemski, Kurt Bedell, Emily Bui, Stanley Perlman, Qihong Zhang, Kai Wang, Val C. Sheffield, Calvin S. Carter
https://doi.org/10.7717/peerj.13277 PubMed 35573180
May 3, 2022
Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway
Fei Sun, Jian Lin Zhou, Si Xing Wei, Ze Wen Jiang, Hao Peng
https://doi.org/10.7717/peerj.13319 PubMed 35529482
April 25, 2022
Effects of cigarette smoking on metabolic activity of lung cancer on baseline 18F-FDG PET/CT
Maoqing Jiang, Xiuyu Guo, Xiaohui Zhang, Qiaoling Gao, Weiqi Mei, Jingfeng Zhang, Jianjun Zheng
https://doi.org/10.7717/peerj.13352 PubMed 35497180
April 22, 2022
Zonula occludens-1 expression is reduced in nasal epithelial cells of allergic rhinitis patients
Che Othman Siti Sarah, Siti Muhamad Nur Husna, Norasnieda Md. Shukri, Kah Keng Wong, Noor Suryani Mohd Ashari
https://doi.org/10.7717/peerj.13314 PubMed 35480562
April 12, 2022
Diurnal pattern of salivary alpha-amylase and cortisol under citric acid stimulation in young adults
Haimei Xie, Xiaomei Zheng, Ye Huang, Weihao Li, Wenkai Wang, Qiao Li, Jiangtao Hou, Lulu Luo, Xiuying Kuang, Chuan-quan Lin
https://doi.org/10.7717/peerj.13178 PubMed 35433126
March 30, 2022
RNA sequencing reveals the emerging role of bronchoalveolar lavage fluid exosome lncRNAs in acute lung injury
Meijuan Song, Xiuwei Zhang, Yizhou Gao, Bing Wan, Jinqiang Wang, Jinghang Li, Yuanyuan Song, Xiaowei Shen, Li Wang, Mao Huang, Xiaowei Wang
https://doi.org/10.7717/peerj.13159 PubMed 35378935
March 17, 2022
A comparative study of the capability of MSCs isolated from different human tissue sources to differentiate into neuronal stem cells and dopaminergic-like cells
Nidaa A. Ababneh, Ban Al-Kurdi, Fatima Jamali, Abdalla Awidi
https://doi.org/10.7717/peerj.13003 PubMed 35341051
March 15, 2022
Predicting population: development and validation of a new predictive nomogram for evaluating medication nonadherence risk in a type 2 diabetes
NaRen QiMuge, Xu Fang, Baocheng Chang, Dong Mei Li, Yuanyuan Li
https://doi.org/10.7717/peerj.13102 PubMed 35310157
March 8, 2022
Increased level of FAM19A5 is associated with cerebral small vessel disease and leads to a better outcome
Zhongnan Hao, Shaonan Yang, Ruihua Yin, Jin Wei, Yuan Wang, Xudong Pan, Aijun Ma
https://doi.org/10.7717/peerj.13101 PubMed 35282278
March 3, 2022
LncRNA CCAT1 facilitates the proliferation, invasion and migration of human laryngeal squamous cell carcinoma cells via the miR-218-5p/BMI1
Jing Hong, Ali Hong, Houshu Tu, Zhichao Wan, Yuqiao Deng, Chengcheng Deng, Bo Tao, Yanjin Yu, Lanfei Zhou
https://doi.org/10.7717/peerj.12961 PubMed 35261819
February 23, 2022
Efficacy of brain natriuretic peptide vs. nicorandil in preventing contrast-induced nephropathy: a network meta-analysis
Ziwei Mei, Songmei Luo, Peipei Chen, Qiankun Zhang, Limei Zhou, Chaoyong Zhu, Hong Zhu, Lie Jin
https://doi.org/10.7717/peerj.12975 PubMed 35228908
February 15, 2022
Human cytomegalovirus infection and its association with gestational diabetes mellitus during pregnancy
Yunyang Wang, Xianjuan Zhang, Xu Zheng, Guanghui Song, Lina Fang, Yangang Wang, Bin Wang
https://doi.org/10.7717/peerj.12934 PubMed 35186501
February 15, 2022
Exploring the mechanism of cordycepin combined with doxorubicin in treating glioblastoma based on network pharmacology and biological verification
Jing Chen, Yuan-Dong Zhuang, Qiang Zhang, Shuang Liu, Bing-Bo Zhuang, Chun-Hua Wang, Ri-Sheng Liang
https://doi.org/10.7717/peerj.12942 PubMed 35186504
February 8, 2022
Antiviral drug discovery by targeting the SARS-CoV-2 polyprotein processing by inhibition of the main protease
Mahmoud Kandeel, Jinsoo Kim, Mahmoud Fayez, Yukio Kitade, Hyung-Joo Kwon
https://doi.org/10.7717/peerj.12929 PubMed 35186496
January 21, 2022
Effectiveness of interactive teaching intervention on medical students’ knowledge and attitudes toward stem cells, their therapeutic uses, and potential research applications
Fayez Abdulrazeq, Khalid A. Kheirallah, Abdel-Hameed Al-Mistarehi, Samir Al Bashir, Mohammad A. ALQudah, Abdallah Alzoubi, Jomana Alsulaiman, Mazhar S. Al Zoubi, Abdulwahab Al-Maamari
https://doi.org/10.7717/peerj.12824 PubMed 35116201
January 11, 2022
Biochemical profile in mixed martial arts athletes
Łukasz Marcin Tota, Szczepan Stanisław Wiecha
https://doi.org/10.7717/peerj.12708 PubMed 35047233
December 20, 2021
Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating
José Alexandre Salerno, Thayana Torquato, Jairo R. Temerozo, Livia Goto-Silva, Karina Karmirian, Mayara A. Mendes, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Letícia R Q. Souza, Isis M. Ornelas, Carla P. Veríssimo, Luiz Guilherme H S. Aragão, Gabriela Vitória, Carolina S G. Pedrosa, Suelen da Silva Gomes Dias, Vinicius Cardoso Soares, Teresa Puig-Pijuan, Vinícius Salazar, Rafael Dariolli, Diogo Biagi, Daniel R. Furtado, Luciana Barreto Chiarini, Helena L. Borges, Patrícia T. Bozza, Marilia Zaluar P. Guimarães, Thiago M.L. Souza, Stevens K. Rehen
https://doi.org/10.7717/peerj.12595 PubMed 35036128
December 13, 2021
Identification of high protein kinase CK2α in HPV(+) oropharyngeal squamous cell carcinoma and correlation with clinical outcomes
Janeen H. Trembley, Bin Li, Betsy T. Kren, Justin Peltola, Juan Manivel, Devi Meyyappan, Amy Gravely, Mark Klein, Khalil Ahmed, Emiro Caicedo-Granados
https://doi.org/10.7717/peerj.12519 PubMed 34993017
October 14, 2021
Betulinic acid decreases lipid accumulation in adipogenesis-induced human mesenchymal stem cells with upregulation of PGC-1α and UCP-1 and post-transcriptional downregulation of adiponectin and leptin secretion
Sasithon Senamontree, Thitiporn Lakthan, Pornsri Charoenpanich, Chanpen Chanchao, Adisri Charoenpanich
https://doi.org/10.7717/peerj.12321 PubMed 34721992
July 16, 2021
Association between Dietary Inflammatory Index and Type 2 diabetes mellitus in Xinjiang Uyghur autonomous region, China
WenHui Fu, Hualian Pei, Nitin Shivappa, James R. Hebert, Tao Luo, Tian Tian, Dilibaier Alimu, Zewen Zhang, Jianghong Dai
https://doi.org/10.7717/peerj.11159 PubMed 34316387
June 18, 2021
The impact of mental and somatic stressors on physical activity and sedentary behaviour in adults with type 2 diabetes mellitus: a diary study
Louise Poppe, Annick L. De Paepe, Dimitri M.L. Van Ryckeghem, Delfien Van Dyck, Iris Maes, Geert Crombez
https://doi.org/10.7717/peerj.11579 PubMed 34178463
May 27, 2021
First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cells
Salomé Vilchez Larrea, Wanda Mariela Valsecchi, Silvia H. Fernández Villamil, Laura I. Lafon Hughes
https://doi.org/10.7717/peerj.11442 PubMed 34123588
May 19, 2021
High fructose exposure modifies the amount of adipocyte-secreted microRNAs into extracellular vesicles in supernatants and plasma
Adrián Hernández-Díazcouder, Javier González-Ramírez, Abraham Giacoman-Martínez, Guillermo Cardoso-Saldaña, Eduardo Martínez-Martínez, Horacio Osorio-Alonso, Ricardo Márquez-Velasco, José L. Sánchez-Gloria, Yaneli Juárez-Vicuña, Guillermo Gonzaga, Laura Gabriela Sánchez-Lozada, Julio César Almanza-Pérez, Fausto Sánchez-Muñoz
https://doi.org/10.7717/peerj.11305 PubMed 34055478
May 18, 2021
Microsatellite instability and Epstein-Barr virus combined with PD-L1 could serve as a potential strategy for predicting the prognosis and efficacy of postoperative chemotherapy in gastric cancer
Na Yang, Yanhua Wu, Meishan Jin, Zhifang Jia, Yueqi Wang, Donghui Cao, Lili Qin, Xueying Wang, Min Zheng, Xueyuan Cao, Jing Jiang
https://doi.org/10.7717/peerj.11481 PubMed 34046266
May 13, 2021
Seasonal variation of 25-Hydroxyvitamin D and indices of carbohydrate and lipid metabolism in postmenopausal women
Anna Huta-Osiecka, Krystian Wochna, Zbigniew Kasprzak, Alicja Nowak
https://doi.org/10.7717/peerj.11341 PubMed 34035990
May 12, 2021
O-GlcNAcylation is a key regulator of multiple cellular metabolic pathways
Hongshuo Zhang, Zhen Li, Yufei Wang, Ying Kong
https://doi.org/10.7717/peerj.11443
April 27, 2021
Dysregulation of miR-381-3p and miR-23b-3p in skeletal muscle could be a possible estimator of early post-mortem interval in rats
Vanessa Martínez-Rivera, Christian A. Cárdenas-Monroy, Oliver Millan-Catalan, Jessica González-Corona, N. Sofia Huerta-Pacheco, Antonio Martínez-Gutiérrez, Alexa Villavicencio-Queijeiro, Carlos Pedraza-Lara, Alfredo Hidalgo-Miranda, María Elena Bravo-Gómez, Carlos Pérez-Plasencia, Mariano Guardado-Estrada
https://doi.org/10.7717/peerj.11102 PubMed 33986977
April 5, 2021
miR-155-5p upregulation ameliorates myocardial insulin resistance via mTOR signaling in chronic alcohol drinking rats
Zhaoping Li, Zhenzhen Hu, Yan Meng, Hongzhao Xu, Yali Wei, Deqiang Shen, Hao Bai, Huacai Yuan, Liyong Chen
https://doi.org/10.7717/peerj.10920 PubMed 33868799
April 2, 2021
Transcriptional profile in rat muscle: down-regulation networks in acute strenuous exercise
Stela Mirla da Silva Felipe, Raquel Martins de Freitas, Emanuel Diego dos Santos Penha, Christina Pacheco, Danilo Lopes Martins, Juliana Osório Alves, Paula Matias Soares, Adriano César Carneiro Loureiro, Tanes Lima, Leonardo R. Silveira, Alex Soares Marreiros Ferraz, Jorge Estefano Santana de Souza, Jose Henrique Leal-Cardoso, Denise P. Carvalho, Vania Marilande Ceccatto
https://doi.org/10.7717/peerj.10500 PubMed 33859869
March 12, 2021
Segmental analysis by speckle-tracking echocardiography of the left ventricle response to isoproterenol in male and female mice
Elisabeth Walsh-Wilkinson, Marie Arsenault, Jacques Couet
https://doi.org/10.7717/peerj.11085 PubMed 33763310
February 2, 2021
Intestinal fatty acid-binding protein, a biomarker of intestinal barrier dysfunction, increases with the progression of type 2 diabetes
Yifeng Wang, Licheng Ding, Jiayue Yang, Lijun Liu, Liang Dong
https://doi.org/10.7717/peerj.10800 PubMed 33604184
February 2, 2021
Undiagnosed cardiovascular risk factors in overweight and obese individuals: a low income country experience
Patricio Alfredo Vallejo-Valdivieso, Graciela Zambrano-Pincay, Alberto Ortiz
https://doi.org/10.7717/peerj.10870 PubMed 33604197
February 1, 2021
Effect of ultra-processed foods consumption on glycemic control and gestational weight gain in pregnant with pregestational diabetes mellitus using carbohydrate counting
Carolina F. M. Silva, Claudia Saunders, Wilza Peres, Bárbara Folino, Taiana Kamel, Mayara Silva dos Santos, Patrícia Padilha
https://doi.org/10.7717/peerj.10514 PubMed 33585080
January 15, 2021
Hyperglycemia in severe traumatic brain injury patients and its association with thirty-day mortality: a prospective observational cohort study in Uganda
Paul Matovu, Musa Kirya, Moses Galukande, Joel Kiryabwire, John Mukisa, William Ocen, Michael Lowery Wilson, Anne Abio, Herman Lule
https://doi.org/10.7717/peerj.10589 PubMed 33520442
January 8, 2021
Silk derived formulations for accelerated wound healing in diabetic mice
Muniba Tariq, Hafiz Muhammad Tahir, Samima Asad Butt, Shaukat Ali, Asma Bashir Ahmad, Chand Raza, Muhammad Summer, Ali Hassan, Junaid Nadeem
https://doi.org/10.7717/peerj.10232 PubMed 33510964
December 16, 2020
Dysregulated levels of glycogen synthase kinase-3β (GSK-3β) and miR-135 in peripheral blood samples of cases with nephrotic syndrome
Mohammadreza Ardalan, Seyyedeh Mina Hejazian, Hassan Fazlazar Sharabiyani, Farahnoosh Farnood, Amirhossein Ghafari Aghdam, Milad Bastami, Elham Ahmadian, Sepideh Zununi Vahed, Magali Cucchiarini
https://doi.org/10.7717/peerj.10377 PubMed 33362958
December 10, 2020
Determinants of behavioural and biological risk factors for cardiovascular diseases from state level STEPS survey (2017–19) in Madhya Pradesh
Arun M. Kokane, Rajnish Joshi, Ashwin Kotnis, Anirban Chatterjee, Kriti Yadav, G Revadi, Ankur Joshi, Abhijit P. Pakhare
https://doi.org/10.7717/peerj.10476 PubMed 33354427
November 24, 2020
HIV-1 promoter is gradually silenced when integrated into BACH2 in Jurkat T-cells
Anne Inderbitzin, Yik Lim Kok, Lisa Jörimann, Audrey Kelley, Kathrin Neumann, Daniel Heinzer, Toni Cathomen, Karin J. Metzner
https://doi.org/10.7717/peerj.10321 PubMed 33282555
November 19, 2020
Four sesquiterpene glycosides from loquat (Eriobotrya japonica) leaf ameliorates palmitic acid-induced insulin resistance and lipid accumulation in HepG2 Cells via AMPK signaling pathway
Jiawei Li, Xiaoqin Ding, Tunyu Jian, Han Lü, Lei Zhao, Jing Li, Yan Liu, Bingru Ren, Jian Chen
https://doi.org/10.7717/peerj.10413 PubMed 33240683
November 3, 2020
Exosomal cargoes in OSCC: current findings and potential functions
Chengzhi Zhao, Geru Zhang, Jialing Liu, Chenghao Zhang, Yang Yao, Wen Liao
https://doi.org/10.7717/peerj.10062 PubMed 33194377
October 22, 2020
Constitution of a comprehensive phytochemical profile and network pharmacology based investigation to decipher molecular mechanisms of Teucrium polium L. in the treatment of type 2 diabetes mellitus
Vahap Murat Kutluay, Neziha Yagmur Diker
https://doi.org/10.7717/peerj.10111 PubMed 33150068
October 14, 2020
Quantile-dependent expressivity of plasma adiponectin concentrations may explain its sex-specific heritability, gene-environment interactions, and genotype-specific response to postprandial lipemia
Paul T. Williams
https://doi.org/10.7717/peerj.10099 PubMed 33088620
September 29, 2020
Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies
Jennifer Enciso, Luis Mendoza, Elena R. Álvarez-Buylla, Rosana Pelayo
https://doi.org/10.7717/peerj.9902 PubMed 33062419
August 28, 2020
Comparison of serum exosome isolation methods on co-precipitated free microRNAs
Yirui Cheng, Xiangyun Qu, Zhaonan Dong, Qingyu Zeng, Xueqing Ma, Yunli Jia, Ruochen Li, Xiaoxu Jiang, Cecilia Williams, Tao Wang, Weiliang Xia
https://doi.org/10.7717/peerj.9434 PubMed 32923177
August 25, 2020
Mitochondrial destiny in type 2 diabetes: the effects of oxidative stress on the dynamics and biogenesis of mitochondria
Daria Skuratovskaia, Alexandra Komar, Maria Vulf, Larisa Litvinova
https://doi.org/10.7717/peerj.9741 PubMed 32904391
August 25, 2020
CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-β2 axis under hypoxia
Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao, Zhijiang Liu, Wenming Chen, Junbo Ge, Bei Shi
https://doi.org/10.7717/peerj.9796 PubMed 32904464
August 24, 2020
High fat-fed GPR55 null mice display impaired glucose tolerance without concomitant changes in energy balance or insulin sensitivity but are less responsive to the effects of the cannabinoids rimonabant or Δ(9)-tetrahydrocannabivarin on weight gain
Edward T. Wargent, Malgorzata Kepczynska, Mohamed Sghaier Zaibi, David C. Hislop, Jonathan R.S. Arch, Claire J. Stocker
https://doi.org/10.7717/peerj.9811 PubMed 32904155
August 14, 2020
Off-target effects of protein tyrosine phosphatase inhibitors on oncostatin M-treated human epidermal keratinocytes: the phosphatase targeting STAT1 remains unknown
Brian V. Hong, Ji H. Lee, Robert H. Rice
https://doi.org/10.7717/peerj.9504 PubMed 32864202
July 20, 2020
Engineering of HN3 increases the tumor targeting specificity of exosomes and upgrade the anti-tumor effect of sorafenib on HuH-7 cells
Cong He, Doulathunnisa Jaffar Ali, Yumin Li, Yanliang Zhu, Bo Sun, Zhongdang Xiao
https://doi.org/10.7717/peerj.9524 PubMed 33062407
July 6, 2020
Novel circulating protein biomarkers for thyroid cancer determined through data-independent acquisition mass spectrometry
Dandan Li, Jie Wu, Zhongjuan Liu, Ling Qiu, Yimin Zhang
https://doi.org/10.7717/peerj.9507 PubMed 32704452
June 29, 2020
Integrative analysis of competitive endogenous RNA network reveals the regulatory role of non-coding RNAs in high-glucose-induced human retinal endothelial cells
Nan-Jue Cao, He-Nan Liu, Feng Dong, Wei Wang, Wei Sun, Gang Wang
https://doi.org/10.7717/peerj.9452 PubMed 32655995
June 23, 2020
SPANXN2 functions a cell migration inhibitor in testicular germ cell tumor cells
Fang Zhu, Hao Bo, Guangmin Liu, Ruixue Li, Zhizhong Liu, Liqing Fan
https://doi.org/10.7717/peerj.9358 PubMed 32612888
June 16, 2020
Combination of ferric ammonium citrate with cytokines involved in apoptosis and insulin secretion of human pancreatic beta cells related to diabetes in thalassemia
Patchara Rattanaporn, Sissades Tongsima, Thomas Mandrup-Poulsen, Saovaros Svasti, Dalina Tanyong
https://doi.org/10.7717/peerj.9298 PubMed 32587797
May 5, 2020
Conditioned medium from M2b macrophages modulates the proliferation, migration, and apoptosis of pulmonary artery smooth muscle cells by deregulating the PI3K/Akt/FoxO3a pathway
Suiqing Huang, Yuan Yue, Kangni Feng, Xiaolin Huang, Huayang Li, Jian Hou, Song Yang, Shaojie Huang, Mengya Liang, Guangxian Chen, Zhongkai Wu
https://doi.org/10.7717/peerj.9110 PubMed 32411539
March 18, 2020
Predictive value of CONUT score combined with serum CA199 levels in postoperative survival of patients with pancreatic ductal adenocarcinoma: a retrospective study
Ankang Wang, Bo Sun, Min Wang, Hao Shi, Zhiwei Huang, Tao He, Qiu Li, Jiaqi Deng, Wenguang Fu, Yu Jiang
https://doi.org/10.7717/peerj.8811 PubMed 32219033
February 20, 2020
Endoplasmic reticulum stress and the protein degradation system in ophthalmic diseases
Jing-Yao Song, Xue-Guang Wang, Zi-Yuan Zhang, Lin Che, Bin Fan, Guang-Yu Li
https://doi.org/10.7717/peerj.8638 PubMed 32117642
January 28, 2020
Moderation effects of food intake on the relationship between urinary microbiota and urinary interleukin-8 in female type 2 diabetic patients
Fengping Liu, Zongxin Ling, Chulei Tang, Fendi Yi, Yong Q. Chen
https://doi.org/10.7717/peerj.8481 PubMed 32025384
September 19, 2019
Identification of pivotal lncRNAs in papillary thyroid cancer using lncRNA–mRNA–miRNA ceRNA network analysis
Weiwei Liang, Fangfang Sun
https://doi.org/10.7717/peerj.7441 PubMed 31579562
September 5, 2019
The heart of a hibernator: EGFR and MAPK signaling in cardiac muscle during the hibernation of thirteen-lined ground squirrels, Ictidomys tridecemlineatus
Christine L. Childers, Shannon N. Tessier, Kenneth B. Storey
https://doi.org/10.7717/peerj.7587 PubMed 31534849
August 12, 2019
Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats
Yan Zhang, Jun Yang, Li Zhuan, Guanghui Zang, Tao Wang, Jihong Liu
https://doi.org/10.7717/peerj.7507 PubMed 31423366
July 29, 2019
Cardioprotective effects of Prolame and SNAP are related with nitric oxide production and with diminution of caspases and calpain-1 activities in reperfused rat hearts
Nadia Giovanna Román-Anguiano, Francisco Correa, Agustina Cano-Martínez, Aurora de la Peña-Díaz, Cecilia Zazueta
https://doi.org/10.7717/peerj.7348 PubMed 31392096
December 4, 2018
Identification of key candidate genes and biological pathways in bladder cancer
Xin Gao, Yinyi Chen, Mei Chen, Shunlan Wang, Xiaohong Wen, Shufang Zhang
https://doi.org/10.7717/peerj.6036 PubMed 30533316
June 11, 2018
Expressional and functional interactions of two Apis cerana cerana olfactory receptors
Lina Guo, Huiting Zhao, Yusuo Jiang
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