18 May 2022

Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway

"Hair loss is a serious cosmetic issue related to the general life of many individuals. Currently, there is no effective remedies on this disorder. This report has shown that melatonin has the capacity to improve the hair growth and also identified the potential mechanism. If this observation is confirmed by other groups, it will provide an additional method to deal with hair loss."

Dunxian Tan, Handling Editor

12 May 2022

Non-destructive monitoring of 3D cell cultures: new technologies and applications

"Cortesi and Giordano review recent advances in 3D culture systems that utilize scaffolds for tissue engineering-based modalities, providing an invaluable resource for approaches that mimic in vivo conditions that allow discovery of cellular activities in the different niches. this field pave the way to"

Joseph Gillespie, Handling Editor

4 May 2022

Transcriptomic signals of mitochondrial dysfunction and OXPHOS dynamics in fast-growth chicken

"Important study that contain crucial data for poultry science."

Vladimir Uversky, Handling Editor

3 May 2022

HIF1α is dispensable for oocyte development and female fertility in mice

"The present study showed that conditional knockout of HIF1α did not affect oocyte maturation, early embryonic development and female fertility. Although the results are negative, they are valuable for researchers in reproductive biology."

Qing-Yuan Sun, Handling Editor

3 May 2022

Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer

"This study makes an useful contribution towards the structural studies of membrane proteins."

Ayyalusamy Ramamoorthy, Handling Editor

3 May 2022

Integrated lipidomics and RNA sequencing analysis reveal novel changes during 3T3-L1 cell adipogenesis

"Obesity can be a problem for human health, and this paper provides important basic knowledge to understand obesity,"

Tokuko Haraguchi, Handling Editor

20 April 2022

Analysis of serum and gene expression profile of cytokines (IL-6, TNF-α and TGF-β1) in chronic hepatitis C virus infection

"adds new information regarding the biology of long term HepC infection"

Howard Young, Handling Editor

11 April 2022

A model of multiple tumor marker for lymph node metastasis assessment in colorectal cancer: a retrospective study

"A new nomogram to predict lymph node metastasis in colorectal cancer has been provided."

Maria Cristina Albertini, Handling Editor

7 April 2022

The regulation of hsacirc_004413 promotes proliferation and drug resistance of gastric cancer cells by acting as a competing endogenous RNA for miR-145-5p

"this article will change the direction of Gastric cancer treatment."

Saima Muzammil, Handling Editor

21 March 2022

Chikungunya virus time course infection of human macrophages reveals intracellular signaling pathways relevant to repurposed therapeutics

"Helps clarify the biology of virus infection"

Howard Young, Handling Editor