13 September 2024

Phytochemical profiling and antioxidant activity assessment of Bellevalia pseudolongipes via liquid chromatography-high-resolution mass spectrometry

"The study of the phytochemical profile of popularly used plants is essential for the bioprospecting of new substances with pharmacological activity. In this article, the authors describe the main components of Bellevalia pseudolongipes, a plant endemic of Turkey."

Eder Lenardão, Handling Editor

10 September 2024

Relationship between ferroptosis and mitophagy in acute lung injury: a mini-review

"Significance: This review is the first to comprehensively describe the link between mitophagy and ferroptosis in Acute Lung Injury via detailing the latest knowledge insights into advances in the roles of mitophagy and ferroptosis in Acute Lung Injury, while exploring the more recently identified novel relationship between mitophagy and ferroptosis involved in Acute Lung Injury. Impact: Doctors specializing in thoracic surgery, respiratory medicine and clinical laboratory medicine will find the review of current scientific literature of particular interest. The exploration of the interaction between mitophagy and ferroptosis contributes to a better understanding of the pathological process of Acute Lung Injury."

Andrew Eamens, Handling Editor

6 September 2024

A lipidomic study on the lens epithelial cells of patients with age related cataracts

"The present study evaluated lipids in the LECs of ARC patients with different lens opacity in order to identify potential metabolic biomarkers of ARC. Their results improve the understanding in ARC and highlight the importance of new methods for its treatment."

Beatriz Redondo, Handling Editor

5 September 2024

Omics approaches to unravel insecticide resistance mechanism in Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae)

Ravinder Kumar, Handling Editor

2 September 2024

A genetic investigation in five Chinese families with keratoconus

"Keratoconus is a common condition, and this paper looks into the possible genes that may be relevant."

Cong-Jun Li, Handling Editor

8 August 2024

Quantitating primer-template interactions using deconstructed PCR

"This article contributes to the understanding of primer/template interaction that can lead to a biased representation of the diversity of microbiomes assessed by metabarcoding."

Marcelino Suzuki, Handling Editor

23 July 2024

An investigation of the pigments, antioxidants and free radical scavenging potential of twenty medicinal weeds found in the southern part of Bangladesh

Nasim Yasin, Handling Editor

5 July 2024

Brazilin cream from Caesalpinia sappan inhibit periodontal disease: in vivo study

Amjad Abu Hasna, Handling Editor

1 July 2024

Diospyros rhodocalyx Kurz induces mitochondrial-mediated apoptosis via BAX, Bcl-2, and caspase-3 pathways in LNCaP human prostate cancer cell line

"The study on Diospyros rhodocalyx Kurz demonstrates its potential as an anti-cancer agent against LNCaP human prostate cancer cells by inducing apoptosis through mitochondrial-mediated pathways. Specifically, the ethyl acetate extract (EADR) increases pro-apoptotic BAX, decreases anti-apoptotic Bcl-2, and activates caspase-3, leading to cell death. The cytotoxic effect of EADR is more pronounced in cancer cells than in normal cells, highlighting its selectivity and potential for therapeutic development. The identification of epilupeol as a key compound further underscores the promise of EADR in prostate cancer treatment, offering a basis for future research and drug development."

Sonia Oliveira, Section Editor

28 June 2024

Effect of glucocorticoid blockade on inflammatory responses to acute sleep fragmentation in male mice

"I feel this manuscript will be highly cited. Nice work and interesting results. "

Manuel Jimenez, Handling Editor