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Background. In recent years, Dengue has been emerging as a global health problem with approximately 2.5 billion people being affected by it .In the last 50 years, the incidence of dengue infection has increased 30-fold, and the World Health Organization (WHO) has estimated that 96 million cases of dengue occur annually. The epidemiology of dengue fever (DF) is complex in the Indian subcontinent as all the four serotypes are circulating. And there is no systematic epidemiological study done on dengue cases in Manipur, a north-eastern state of India. This study is therefore done to report observations on dengue cases from a virus diagnostic and research laboratory of Manipur to present an epidemiological scenario of the state for the last three years. Method. We used the dengue data extracted from the laboratory register of Viral Research and Diagnostic Laboratory (VRDL) from 2016 to 2018. All suspected outpatient and inpatients dengue cases from public and private health services are included in the VRDL database whose informed consent were obtained. We evaluated the overall features of the data for generating seasonal pattern, geographical pattern, gender wise distribution, age wise distribution and seroprevelance pattern of dengue cases for the study period from 2016 to 2018. Results. A total of 1689 cases of suspected patients of dengue virus infection were tested for dengue ELISA test and 272(16.10%) samples were found to be seropositive. The month wise distribution of dengue cases is quite an interesting as the three years of study shows variant pattern in observation. In all the three years dengue seropositive cases were seen higher in male population. But there is no significant value to the positivity of dengue seropositive towards male than female (The chi-square statistic is 2.1314.The p-value is .344481. The result is not significant at p < .05.). Conclusion. Our study presents a comparative epidemiological study on seroprevelance of dengue in the state of Manipur from the year 2016 to 2018. The findings in the present study extend the knowledge of the geographical distribution and seroprevelance of dengue in the state of Manipur for the last three years. This is an attempt to present epidemiological dengue seroprevelance in the state of Manipur which in future would be a reference from public health concerns for taking up necessary action plan to curtail the spread of dengue.
This is a submission to PeerJ for review.
The excel sheets are raw data compilation for dengue cases from the year 2016 to 2018
Sheet 1 to 3 indicates every case of dengue under study from the year 2016 to 2018. The sheet 4 is a tabulation data while the last sheet is data analysis.