Preprints (not yet peer-reviewed)

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Background. Ruminants are successful herbivorous mammals, in part due to their specialized forestomachs, the rumen complex, which facilitates the conversion of feed to soluble nutrients by micro-organisms. Is the rumen complex a modified stomach expressing new...

["Agricultural Science","Bioinformatics","Evolutionary Studies","Genomics","Veterinary Medicine"]
doi:10.7287/peerj.preprints.1742v1
124 downloads
332 views

Data is the cornerstone of the modern academic industry, like a constant production line of consumable goods packaged with a veneer of statistical techniques. Biomedical and psychological sciences invert the traditional logic of the physical sciences where hypotheses...

["Science Policy","Statistics"]
doi:10.7287/peerj.preprints.1655v2
79 downloads
126 views

PhilDB is an open-source time series database that supports storage of time series datasets that are dynamic, that is it records updates to existing values in a log as they occur. PhilDB eases loading of data for the user by utilising an intelligent data write...

["Data Science","Databases"]
doi:10.7287/peerj.preprints.1488v2
27 downloads
107 views

We have collected computed barrier heights and reaction energies (and associated model structures) for five enzymes from studies published by Himo and co-workers. Using this data, obtained at the B3LYP/6- 311+G(2d,2p)[LANL2DZ]//B3LYP/6-31G(d,p) level of theory,...

["Biophysics","Computational Biology"]
doi:10.7287/peerj.preprints.1741v1
7 downloads
45 views

The COBRA protein is found only in higher plants and algae, and has been implicated in cellulose synthesis, but its specific function remains unknown. To shed light on COBRA function we tested the ability of putative Arabidopsis COBRA orthologs to complement mutations...

["Plant Science"]
doi:10.7287/peerj.preprints.1740v1
71 downloads
411 views

Heavy losses incited yearly by Alternaria brassicicola on the vegetable Brassicaceae – have prompted our search for sources of genetic resistance against the pathogen and the resultant disease, dark leaf spot. We optimized several parameters to test the performance...

["Agricultural Science","Cell Biology","Microbiology","Plant Science"]
doi:10.7287/peerj.preprints.1360v2
7 downloads
59 views

Scleractinian corals play a critical role in tropical marine ecosystems by providing essential structure and food for coral reef inhabitants. However, recent investigations have found an alarming increase in coral losses from a variety of stressors, which threatens...

["Biochemistry","Environmental Sciences","Marine Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.1738v1
8 downloads
45 views

Microgeographic variation in fitness-relevant traits may be more common than previously appreciated. The fitness of many vertebrates is directly related to their locomotor capacity, a whole-organism trait integrating behavior, morphology, and physiology. Because...

["Animal Behavior","Conservation Biology","Ecology","Coupled Natural and Human Systems"]
doi:10.7287/peerj.preprints.1737v1
10 downloads
39 views

Here we question the generality of the conventional definition of a native conformation –as the 3-dimensional conformation of an entire globular polypeptide molecule. Although considered common knowledge, and thus not explicitly stated in modern writings, this...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Molecular Biology"]
doi:10.7287/peerj.preprints.1735v1
28 downloads
77 views

Aggregation during dispersal from source to settlement sites can allow persistence of weak competitors, by creating conditions where stronger competitors are more likely to interact with conspecifics than with less competitive heterospecifics. However, different...

["Biodiversity","Ecology","Marine Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.1734v1
7,685 downloads
36,758 views

Biases against women in the workplace have been documented in a variety of studies. This paper presents the largest study to date on gender bias, where we compare acceptance rates of contributions from men versus women in an open source software community. Surprisingly,...

["Human-Computer Interaction","Social Computing","Programming Languages","Software Engineering"]
doi:10.7287/peerj.preprints.1733v1
8 downloads
41 views

Background. The need for timely, ethical, and high-quality reporting of clinical trial results has seen a rise in demand for publication professionals. These publication experts, who are not ghostwriters, work with leading medical researchers and funders around...

["Science and Medical Education"]
doi:10.7287/peerj.preprints.1732v1
50 downloads
386 views

Background. Increased interest in luxury products and Traditional Chinese Medicine, associated with economic growth in China, has been linked to depletion of both terrestrial and marine wildlife. Among the most rapidly emerging concerns with respect to these markets...

["Aquaculture, Fisheries and Fish Science","Conservation Biology","Marine Biology","Science Policy"]
doi:10.7287/peerj.preprints.1731v1
5 downloads
29 views

Ishikawa endometrial epithelial cells are capable of differentiation from monolayer cells into fluid-enclosing hemispheres through a surprisingly complex series of structural changes as discussed in this and in two accompanying papers (Fleming, 2016a; Fleming 2016b)....

["Cell Biology","Developmental Biology"]
doi:10.7287/peerj.preprints.1730v1
7 downloads
24 views

Pyknosis, karyorrhexis and karyolysis, harbingers of programmed cell death in many systems, appear to be driving forces that transform Ishikawa monolayer epithelial cells into differentiated dome cells. The heterochromatin affected by these process is contained...

["Cell Biology","Developmental Biology"]
doi:10.7287/peerj.preprints.1729v1
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