Visitors   Views   Downloads
"PeerJ Preprints" is a venue for early communication or feedback before peer review. Data may be preliminary.

A peer-reviewed article of this Preprint also exists.

View peer-reviewed version

Additional Information

Competing Interests

W Koldingsnes has received consulting fees, speaking fees and travel grants from Hoffmann-La Roche.

Author Contributions

Emilio Besada conceived and designed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Wenche Koldingsnes reviewed drafts of the paper.

Johannes C Nossent wrote the paper, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

All patients gave informed written consent at registry inclusion according to the declaration of Helsinki. The study did not require formal ethical approval in accordance with the standards applied in Norway.


The authors declare there was no funding for this work.

Add your feedback

Before adding feedback, consider if it can be asked as a question instead, and if so then use the Question tab. Pointing out typos is fine, but authors are encouraged to accept only substantially helpful feedback.

Some Markdown syntax is allowed: _italic_ **bold** ^superscript^ ~subscript~ %%blockquote%% [link text](link URL)
By posting this you agree to PeerJ's commenting policies