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Additional Information

Competing Interests

The authors declare they have no competing interests.

Author Contributions

Orlando Torres-Fernández conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper.

Jeison Monroy-Gómez performed the experiments, analyzed the data, prepared figures and/or tables, reviewed drafts of the paper.

Ladys E Sarmiento performed the experiments, analyzed the data, prepared figures and/or tables, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

This work was approved by the Ethics Committee of the Instituto Nacional de Salud (Bogotá, Colombia) according to Act No. 8 October 13 2011

Funding

This work was funded by Departamento Administrativo de Ciencias, Tecnología e Innovación COLCIENCIAS and the Instituto Nacional de Salud (INS, Colombia). Code of Grant 210454531601. Contract 378/2011. The participation of the second author (JMG) was financed by COLCIENCIAS and the INS under the 'Jóvenes Investigadores e Innovadores' Program (Contract 0237/2012). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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