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Requirements for data integration platforms in biomedical research networks: A reference model

,
  Institute of Medical Biometry and Informatics, Heidelberg University, Heidelberg, Germany
DOI
10.7287/peerj.preprints.689v1
Published
Accepted
Subject Areas
Bioinformatics, Computational Science
Keywords
research network, reference model, data integration, biomedical informatics, service-oriented architecture
Copyright
© 2014 Ganzinger et al.
Licence
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ PrePrints) and either DOI or URL of the article must be cited.
Cite this article
Ganzinger M, Knaup P. 2014. Requirements for data integration platforms in biomedical research networks: A reference model. PeerJ PrePrints 2:e689v1

Abstract

Biomedical research networks need to integrate research data among their members and with external partners. To support such data sharing activities, adequate information technology infrastructure is necessary. To facilitate the establishments of such an infrastructure, we developed a reference model for requirements. The reference model consists of five reference goals and 15 reference requirements. Using the Unified Modeling Language, the goals and requirements are set into relation to each other. In addition, all goals and requirements are described textually in tables. This reference model can be used by research networks as a basis for the resource efficient acquisition of their project specific requirements. Further, a concrete instance of the reference model is described for a research network on liver cancer. The reference model is transferred into a requirements model of the specific network. Based on this concrete requirements model, a service-oriented information technology architecture is derived and also described in this paper.

Author Comment

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Supplemental Information

SI1: Reference goals and requirements

DOI: 10.7287/peerj.preprints.689v1/supp-1

SI2: Goals and requirements of a research network on liver cancer

DOI: 10.7287/peerj.preprints.689v1/supp-2

Additional Information

Competing Interests

The authors declare they have no competing interests.

Author Contributions

Matthias Ganzinger conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Petra Knaup wrote the paper, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

For the research described in this paper, ethics approval was not deemed necessary. This work involved no human subjects in the sense of medical research, as e.g. covered by the Declaration of Helsinki (World Medical Association, 2013). At no time patients were included for survey or interview. Data was only acquired from scientists regarding their work and data, but no personal or patient related data were gathered. Participants were not required to participate in this study. They consented by returning the questionnaire. No research was conducted outside Germany, the authors’ country of residence. However, in other countries the approval of an institutional review board or other authority might be necessary to apply the reference model.

Funding

This work was funded by the SFB/TRR 77 “Liver Cancer. From Molecular Pathogenesis to Targeted Therapies” of the Deutsche Forschungsgemeinschaft (DFG, http://www.dfg.de). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Requirements for data integration platforms in biomedical research networks: A reference model
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