Requirements for data integration platforms in biomedical research networks: A reference model
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Abstract
Biomedical research networks need to integrate research data among their members and with external partners. To support such data sharing activities, adequate information technology infrastructure is necessary. To facilitate the establishments of such an infrastructure, we developed a reference model for requirements. The reference model consists of five reference goals and 15 reference requirements. Using the Unified Modeling Language, the goals and requirements are set into relation to each other. In addition, all goals and requirements are described textually in tables. This reference model can be used by research networks as a basis for the resource efficient acquisition of their project specific requirements. Further, a concrete instance of the reference model is described for a research network on liver cancer. The reference model is transferred into a requirements model of the specific network. Based on this concrete requirements model, a service-oriented information technology architecture is derived and also described in this paper.
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2014. Requirements for data integration platforms in biomedical research networks: A reference model. PeerJ PrePrints 2:e689v1 https://doi.org/10.7287/peerj.preprints.689v1note This preprint is not peer-reviewed. You may wish to reference the subsequent peer-reviewed version of this article.
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Supplemental Information
SI2: Goals and requirements of a research network on liver cancer
Additional Information
Competing Interests
The authors declare they have no competing interests.
Author Contributions
Matthias Ganzinger conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.
Petra Knaup wrote the paper, reviewed drafts of the paper.
Human Ethics
The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):
For the research described in this paper, ethics approval was not deemed necessary. This work involved no human subjects in the sense of medical research, as e.g. covered by the Declaration of Helsinki (World Medical Association, 2013). At no time patients were included for survey or interview. Data was only acquired from scientists regarding their work and data, but no personal or patient related data were gathered. Participants were not required to participate in this study. They consented by returning the questionnaire. No research was conducted outside Germany, the authors’ country of residence. However, in other countries the approval of an institutional review board or other authority might be necessary to apply the reference model.
Funding
This work was funded by the SFB/TRR 77 “Liver Cancer. From Molecular Pathogenesis to Targeted Therapies” of the Deutsche Forschungsgemeinschaft (DFG, http://www.dfg.de). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
