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A sustainable synthetic biology approach for the control of the invasive golden mussel (Limnoperna fortunei)

, , , , , , ,
1 Carlos Chagas Filho Biophysics Institute, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
2 Bio Bureau Biotecnologia, Rio de Janeiro, RJ, Brasil
3 Department of Science and Technological Innovation, Universitá del Piemonte Orientale Amedeo Avogadro, Alessandria, Italy
4 Department of Life Sciences, Imperial College London, London, United Kingdom
5 CTG Brasil, São Paulo, SP, Brasil
DOI
10.7287/peerj.preprints.27164v1
Published
Accepted
Subject Areas
Biodiversity, Conservation Biology, Molecular Biology, Synthetic Biology, Environmental Impacts
Keywords
Golden mussel, Limnoperna fortunei, Synthetic biology, Gene drive, Biological invasion, CRISPR-Cas9, South America, Business Model Canvas
Copyright
© 2018 Rebelo et al.
Licence
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
Cite this article
Rebelo MF, Afonso LF, Americo JA, da Silva L, Neto JLB, Dondero F, Crisanti A, Zhang Q. 2018. A sustainable synthetic biology approach for the control of the invasive golden mussel (Limnoperna fortunei) PeerJ Preprints 6:e27164v1

Abstract

The recent development of the CRISPR-Cas9-based gene drive has created the conditions to seriously consider this technology to solve one of the major environmental challenges in biodiversity conservation i.e. the control of invasive species. There is no efficient control method for golden mussel infestation available so far. Here we discuss the technical and economic feasibility of using a synthetic biology based approach to fight and control the invasive mussel Limnoperna fortunei in South American rivers and reservoirs.

Author Comment

This is a preprint submission to PeerJ Preprints.

Supplemental Information

Golden mussel disinfestation Business Model Canvas (BMC) description

DOI: 10.7287/peerj.preprints.27164v1/supp-1

Golden mussel disinfestation Business Model Canvas (BMC)

DOI: 10.7287/peerj.preprints.27164v1/supp-2

Additional Information

Competing Interests

The authors disclose the following potential competing interests. Juliana A Americo and Lucas da Silva are researchers employed by Bio Bureau Biotecnologia which is developing products related to the research being reported. Mauro F Rebelo and José L B Neto have equity interest and serve as board members of Bio Bureau Biotecnologia. Qiaoying Zhang is part of the R&D team employed by CTG Brasil, the sponsor who funded the research reported in this publication. Luana F Afonso, Francesco Dondero and Andrea Crisanti declare that they have no competing interests.

Author Contributions

Mauro F Rebelo conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Luana F Afonso analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Juliana A Americo conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Lucas da Silva conceived and designed the experiments, performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

José L B Neto conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools.

Francesco Dondero analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper.

Andrea Crisanti analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper.

Qiaoying Zhang analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper.

Data Deposition

The following information was supplied regarding data availability:

The research in this article did not generate any data or code.

Funding

This work was supported by Brazillian National Electric Energy Agency ANEEL R&D program through grant PD-075 (PD-07514-0002/2017). Qiaoying Zhang is part of the R&D team employed by CTG Brasil, the sponsor who funded the research reported in this publication and provided market data and helped preparing the manuscript.

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A sustainable synthetic biology approach for the control of the invasive golden mussel (Limnoperna fortunei)
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