Conserved domain and structure analysis of a putative polyphosphate kinase from Buruli ulcer causing bacterium
- Published
- Accepted
- Subject Areas
- Bioinformatics, Biophysics, Computational Biology, Genomics, Microbiology
- Keywords
- Computational sequence analysis, Homology modeling, Dynamics simulation, Mycobacterium ulcerans, polyphosphate kinase, Molecular Operating Environment
- Copyright
- © 2016 Basharat
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
- Cite this article
- 2016. Conserved domain and structure analysis of a putative polyphosphate kinase from Buruli ulcer causing bacterium. PeerJ Preprints 4:e2296v1 https://doi.org/10.7287/peerj.preprints.2296v1
Abstract
With increasing sophistication of instruments and techniques, in addition to the increment in intricacies, girth and complexities of the problems being addressed, simple methods (especially computational biology techniques) are being overlooked, replaced or phased out. One such technique on the twilight of survival is simple computational analysis of protein sequence i.e. property determination, homology modeling etc. Manuscripts reporting solely such type of analysis face upfront rejection, although some exceptions might exist. Only some predatory or beginner journals might accept such publications. This continues despite the fact that simple, cost effective, quick computational analysis of protein sequence has its merits and paves way for further research. This report is basically an attempt to keep the dying venture of protein structure modeling alive.
Author Comment
This is a preprint submission to PeerJ Preprints. This preprint version may contain grammatical and proofreading mistakes. Errors and omissions excepted.