Surgical technique´s influence on overall survival, disease free interval and new lesion development interval in dogs with mammary tumors
- Published
- Accepted
- Subject Areas
- Veterinary Medicine, Oncology, Surgery and Surgical Specialties
- Keywords
- Dogs, Surgery, Mammary neoplasm, Lumpectomy, Mammectomy, Mastectomy
- Copyright
- © 2013 dos Santos Horta et al.
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Cite this article
- 2013. Surgical technique´s influence on overall survival, disease free interval and new lesion development interval in dogs with mammary tumors. PeerJ PrePrints 1:e143v1 https://doi.org/10.7287/peerj.preprints.143v1
Abstract
Mammary gland tumors represent 42% of all tumors in the bitch. Although there are numerous studies about disease development and progression, some questions remain concerning the surgical treatment. Many surgical techniques may be used for the treatment of canine mammary tumors similar to Medicine, the advantages and disadvantages of each procedure have been extensively discussed. The purpose of this study is to evaluate the influence of surgical procedure on survival, disease free interval and new lesion development interval in dogs with mammary tumors treated according to the biological behavior of these lesions. For this, 143 intact bitches were submitted to surgery for the treatment of mammary tumors between 2007 and 2011. Removal of mammary tumors was performed through the simplest and less invasive surgical procedure necessary for the complete removal of all tumors and main known lymphatic connections between affected glands: lumpectomy, mammectomy, regional mastectomy (including abdominal cranial mammary gland or not) or radical mastectomy. Mean clinical follow-up was 738.5 days. Considering only the first surgical event, 84.6% of animals had more than one mammary tumor, and 52.5% had tumors in both mammary chains. Comparing surgical techniques, there was no difference in ipsilateral and contralateral tumor development. Only 33 dogs developed new lesions in remaining mammary tissue, without correlation with primary lesion. Surgical technique had no effect on overall survival, disease-free interval and new lesion development interval in patients on this study, treated according to oncological surgery principles and established prognostic factors for mammary gland tumors in dogs. It is important to consider these results when deciding on the surgical management of dogs with mammary tumors, to avoid aggressive surgical procedures that will not translate into clinical advantages to the patient.
Author Comment
This article is the result of a survey of 143 dogs that were not spayed during the experiment. It demonstrates, following our expectations that the surgical technique does not influence the regional disease control, since some prognostic factors are considered and respected.
