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Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Nobuyuki Sano conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables.

Makoto Kyougoku conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

This study was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of the Kibi International University (No. 13-34). In addition, we were approval by the facility directors of the institutions that cooperated in this study. We explained to participants that they could freely decide whether to participate in the study and could refuse to answer the questionnaire during this study. We completely protected the privacy of personal information. Furthermore, we obtained written informed consent from all participants.

Funding

The authors received no funding for this work.


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