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Nikolajs Sjakste
PeerJ Editor, Author & Reviewer
1,915 Points

Contributions by role

Author 435
Preprint Author 35
Reviewer 45
Editor 1,400

Contributions by subject area

Biophysics
Cell Biology
Molecular Biology
Genomics
Plant Science
Biochemistry
Diabetes and Endocrinology
Ophthalmology
Drugs and Devices
Translational Medicine
Ecology
Marine Biology
Climate Change Biology
Clinical Trials
Internal Medicine
Otorhinolaryngology
Biotechnology
Microbiology
Neuroscience
Toxicology
Histology
Respiratory Medicine
Dentistry
Bioinformatics
Genetics
Metabolic Sciences
Hematology
Medical Genetics
Neurology
Nutrition
Public Health
Epidemiology

Nikolajs Sjakste

PeerJ Editor, Author & Reviewer

Summary

Experience

1978 -1987; Researcher in the Cancer Cell Chemistry Laboratory, Institute of Experimental and Clinical Medicine, Riga, Latvia.
Professor of Medical Biochemistry and Medical Genetics, University of Latvia, Faculty of Medicine (since 1998). Address: Jelgavas Street 1, Riga LV1004 Latvia. Chief of the Department of Medical Biochemistry (2011).
Leading researcher (since 2011) and Head of the Biochemistry Group, Department of Medicinal Chemistry, Latvian Institute of Organic Synthesis (since 1990).
1995 and 1997 “Red position” of CNRS 1993-1998; Institut Jacques Monod, Université Paris VII, Laboratoire de Biochimie de Différentiation, Paris, France.

Education:

Degree of Doctor of Biological Sciences (Dr. habil.), 1992, Institute of Experimental Medicine, St.-Petersburg, Russia. Degree of Candidate of Biological Sciences (Ph. D.), 1984, Cancer Research Centre, Moscow, Russia. Diploma with Distinction in Medical Biophysics, graduated from the Medico-Biological faculty of the 2nd Moscow Medical Institute, Moscow, Russia, 1978.

Biochemistry Biomolecules Biophysics Cell Biology Diabetes & Endocrinology Genomics Molecular Biology Otorhinolaryngology UV-Visible Spectroscopy

Editorial Board Member

PeerJ - the Journal of Life & Environmental Sciences

Past or current institution affiliations

University of Latvia

Work details

Professor, Head of the Medical Biochemistry Department

University of Latvia
August 1997
Faculty of Medicine
Teaching Basics of Biochemistry, Medical Biochemistry and Hereditary Diseases to students in Medicine, Dentistry and Pharmacy. Research on interaction of small organic molecules with DNA, DNA integrity, genomics

Websites

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PeerJ Contributions

  • Articles 4
  • Preprints 1
  • Edited 13
July 19, 2022
Ubiquitin-proteasome system in diabetic retinopathy
Zane Svikle, Beate Peterfelde, Nikolajs Sjakste, Kristine Baumane, Rasa Verkauskiene, Chi-Juei Jeng, Jelizaveta Sokolovska
https://doi.org/10.7717/peerj.13715 PubMed 35873915
November 10, 2020
Spectroscopic and electrochemical study of interactions between DNA and different salts of 1,4-dihydropyridine AV-153
Elina Leonova, Karlis Shvirksts, Vitalijs Borisovs, Edgars Smelovs, Jelizaveta Sokolovska, Egils Bisenieks, Gunars Duburs, Mara Grube, Nikolajs Sjakste
https://doi.org/10.7717/peerj.10061 PubMed 33240591
February 18, 2020
Tight DNA-protein complexes isolated from barley seedlings are rich in potential guanine quadruplex sequences
Tatjana Sjakste, Elina Leonova, Rudolfs Petrovs, Ilva Trapina, Marion S. Röder, Nikolajs Sjakste
https://doi.org/10.7717/peerj.8569 PubMed 32110488
April 25, 2018
Study of interaction of antimutagenic 1,4-dihydropyridine AV-153-Na with DNA-damaging molecules and its impact on DNA repair activity
Elina Leonova, Evita Rostoka, Sylvie Sauvaigo, Larisa Baumane, Turs Selga, Nikolajs Sjakste
https://doi.org/10.7717/peerj.4609 PubMed 29713564
October 4, 2017 - Version: 1
Interaction of antimutagenic 1,4-dihydropyridine AV-153-Na with DNA and DNA-damaging molecules and its impact on DNA repair activity
Elina Leonova, Evita Rostoka, Sylvie Sauvaigo, Edgars Smelovs, Larisa Baumane, Vitalijs Borisovs, Turs Selga, Nikolajs Sjakste
https://doi.org/10.7287/peerj.preprints.3317v1

Academic Editor on

October 24, 2024
Association analysis of MTHFR (rs1801133 and rs1801131) gene polymorphism towards the development of type 2 diabetes mellitus in Dali area population from Yunnan Province, China
Yongxin Liu, Genyuan Pu, Caiting Yang, Yuqing Wang, Kaitai Jin, Shengrong Wang, Xiao Liang, Shenghe Hu, Shuguang Sun, Mingming Lai
https://doi.org/10.7717/peerj.18334 PubMed 39465169
August 21, 2023
Crown-of-thorns starfish spines secrete defence proteins
Adam K. Hillberg, Meaghan K. Smith, Blake S. Lausen, Saowaros Suwansa-ard, Ryan Johnston, Shahida A. Mitu, Leah E. MacDonald, Min Zhao, Cherie A. Motti, Tianfang Wang, Abigail Elizur, Keisuke Nakashima, Noriyuki Satoh, Scott F. Cummins
https://doi.org/10.7717/peerj.15689 PubMed 37637177
November 11, 2021
The leukocyte telomere length, single nucleotide polymorphisms near TERC gene and risk of COPD
Tanya Tacheva, Shanbeh Zienolddiny, Dimo Dimov, Denitsa Vlaykova, Tatyana Vlaykova
https://doi.org/10.7717/peerj.12190 PubMed 34824901
September 6, 2021
Investigation of multiple sclerosis-related pathways through the integration of genomic and proteomic data
Elif Everest, Ege Ülgen, Ugur Uygunoglu, Melih Tutuncu, Sabahattin Saip, Osman Uğur Sezerman, Aksel Siva, Eda Tahir Turanli
https://doi.org/10.7717/peerj.11922 PubMed 39544199
August 9, 2021
Therapeutic effects of astragaloside IV and Astragalus spinosus saponins against bisphenol A-induced neurotoxicity and DNA damage in rats
Amina E. Essawy, Heba-Tallah Abd Elrahim Abd Elkader, Omaima A. Khamiss, Saber Mohamed Eweda, Heba Mohamed Abdou
https://doi.org/10.7717/peerj.11930 PubMed 34434659
June 22, 2021
The protective effect of Moringa oleifera plant extract against glutamate-induced DNA damage and reduced cell viability in a primary retinal ganglion cell line
Musarat Amina, Ramesa Shafi Bhat, Abeer M. Al-Dbass, Nawal M. Musayeib, Rania Fahmy, Leen Alhadlaq, Afaf El-Ansary
https://doi.org/10.7717/peerj.11569 PubMed 34221717
June 9, 2021
Expression of autophagy and apoptosis-related factors in the periodontal tissue of experimental diabetic rats: a histomorphometric, microtomographic and immunohistochemical study
Youmin Mei, Xiang Shen, Xiaoqian Wang, Min Zhang, Qiao Li, Junyi Yan, Jiali Xu, Yan Xu
https://doi.org/10.7717/peerj.11577 PubMed 34178461
April 1, 2021
Liraglutide-induced structural modulation of the gut microbiota in patients with type 2 diabetes mellitus
Junjie Shang, Fang Liu, Bing Zhang, Kunlun Dong, Man Lu, Rongfeng Jiang, Yue Xu, Le Diao, Jiangman Zhao, Hui Tang
https://doi.org/10.7717/peerj.11128 PubMed 33850659
March 24, 2021
Characteristics of the gut microbiome in patients with prediabetes and type 2 diabetes
Zewen Zhang, Tian Tian, Zhen Chen, Lirong Liu, Tao Luo, Jianghong Dai
https://doi.org/10.7717/peerj.10952 PubMed 33828910
July 31, 2020
Relationship between iron status markers and insulin resistance: an exploratory study in subjects with excess body weight
M. Pilar Vaquero, Daniel Martínez-Maqueda, Angélica Gallego-Narbón, Belén Zapatera, Jara Pérez-Jiménez
https://doi.org/10.7717/peerj.9528 PubMed 32821534
June 15, 2020
A potential role for Galectin-3 inhibitors in the treatment of COVID-19
John L. Caniglia, Maheedhara R. Guda, Swapna Asuthkar, Andrew J. Tsung, Kiran K. Velpula
https://doi.org/10.7717/peerj.9392 PubMed 32587806
April 10, 2020
Effects of preservation duration at 4 °C on the quality of RNA in rabbit blood specimens
Jiaojiao Song, Junmei Zhou
https://doi.org/10.7717/peerj.8940 PubMed 32309050
February 12, 2020
Comprehensive analysis of long non-coding RNAs and mRNAs in skeletal muscle of diabetic Goto-Kakizaki rats during the early stage of type 2 diabetes
Wenlu Zhang, Yunmeng Bai, Zixi Chen, Xingsong Li, Shuying Fu, Lizhen Huang, Shudai Lin, Hongli Du
https://doi.org/10.7717/peerj.8548 PubMed 32095365