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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Artur Bąk conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Jakub Segen conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Kamil Wereszczyński conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Pawel Mielnik conceived and designed the experiments, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Marcin Fojcik conceived and designed the experiments, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Marek Kulbacki conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Regional Committee for Medical and Health Research Ethics, Region west, Norway has approved the study (ref. 2013/743).

Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Regional komité for medisinsk og helsefaglig forskningsetikk (REK vest)

Data Deposition

The following information was supplied regarding data availability:

Figshare: https://figshare.com/s/338c4add6221c0230ce0

Funding

The research project MEDUSA has received funding from the Polish-Norwegian Research Programme operated by the National Center for Research and Development under the Norwegian Financial Mechanism 2009-2014 in the frame of Project Contract No. Pol-Nor/204256/16/2013. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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