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Additional Information

Competing Interests

The authors declare no competing financial interests.

Author Contributions

Bartram L Smith conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Guifang Chen performed the experiments.

Claus O Wilke conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Robert M Krug conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Data Deposition

The following information was supplied regarding data availability:

Only the abstract is being submitted

Funding

This work was funded by NIH grant AI11772 and NIH grant R01 GM088344. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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