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The investigation of copper-ion coordination to amyloid-beta and potential chelation materials for the treatment of Alzheimer’s disease

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73 days ago
The investigation of metal-ion coordination to amyloid-beta and potential chelation materials for the treatment of Alzheimer’s disease https://t.co/rbaoH3tkNS https://t.co/I7bpFjxkio
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Supplemental Information

Amyloid-Beta Low pH and High pH metal interactions

The etotal represents the total energy of the complex

DOI: 10.7287/peerj.preprints.27942v2/supp-1

Additional Information

Competing Interests

Dr. Luo is employed by National Graphene Research and Development Center and Neha Pavuluru is a mentee under Dr. Luo.

Author Contributions

Neha Pavuluru conceived and designed the experiments, performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper.

Xuan Luo conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Data Deposition

The following information was supplied regarding data availability:

The raw data code files are used to find the total energies of the metal and abeta complexes in both the low-pH coordination sphere and the high-pH coordination sphere.

Funding

The authors received no funding for this work.


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