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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Paweł Woźniak conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Malgorzata Kotulska conceived and designed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper.

Gert Vriend conceived and designed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper.

Data Deposition

The following information was supplied regarding data availability:

All data are available from http://comprec-lin.iiar.pwr.edu.pl/dcaVSmisfolds/ and http://swift.cmbi.ru.nl/dcaVSmisfolds/.

Funding

The work of PPW and MK was partially supported by Statuary Funds. The work of PPW was also partially funded by the Polish National Science Centre (Etiuda 4, DEC-2016/20/T/NZ1/00514). The work of GV was supported by the funding from the EU project NewProt (289350). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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