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Supplemental Information

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Takuro Uehara conceived and designed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Takahiro Tsuge conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables.

Takahiro Ota conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

An approval from the review board is not mandatory at my university (see the attached confidential supplemental file in Japanese). Instead, it recommends checking items to see if a study needs to be approved by the committee. Checking the items, as the attached supplemental file, our study is exempt from the review regarding risk, informed consent, privacy, fraud, conflict of interest, and rewards.

Data Deposition

The following information was supplied regarding data availability:

We plan to make our raw data available but it has not been confirmed yet.

Funding

This research was supported by the Environment Research and Technology Development Fund (S-13) of the Ministry of the Environment, Japan. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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