Novel degradation pathway of 2-chloro-4-aminophenol in Arthrobacter sp. SPG
Department of Plant Science, MJP Rohilkhand University, Bareilly, India
- Published
- Accepted
- Subject Areas
- Agricultural Science, Biochemistry, Biotechnology, Environmental Sciences, Microbiology
- Keywords
- Biodegradation, Bioremediation, 2-chloro-4-aminophenol, 4-chloro-2-aminophenol, hydroquinone, chlorohydroquinone, Arthrobacter, Metabolic pathway
- Copyright
- © 2014 Arora et al.
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Cite this article
- 2014. Novel degradation pathway of 2-chloro-4-aminophenol in Arthrobacter sp. SPG. PeerJ PrePrints 2:e194v1 https://doi.org/10.7287/peerj.preprints.194v1
Abstract
A novel degradation pathway of 2-chloro-4-aminophenol (2C4AP) was studied in an Arthrobacter sp. SPG that utilized 2C4AP as a sole carbon and energy source. The 2C4AP degradation was initiated by a 2C4AP-deaminase that catalyzed the conversion of 2C4AP into chlorohydroquinone (CHQ) with removal of ammonium ion. In the next step, a CHQ-dehalogenase catalyzed the dehalogenation of CHQ to hydroquinone (HQ). The further degradation of HQ was proceeded with ring cleavage and the formation of γ-hydroxymuconic semialdehyde. This is the first report of degradation of 2C4AP by any bacteria.