This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ PrePrints) and either DOI or URL of the article must be cited.
Cite this article
Allen M, Fardo F, Dietz M, Hillebrandt HF, Rees G, Roepstorff A. (2015) Evidence for embodied predictive coding: the anterior insula coordinates cortical processing of tactile deviancy. PeerJ PrePrints3:e1203v1https://doi.org/10.7287/peerj.preprints.1203v1
Embodied awareness is the pervasive, multimodal self-awareness that is thought to form the foundation of emotion. This awareness was recently proposed to rely on the anterior insular cortex (AIC) comparing expected and actual bodily signals arising in prefrontal and sensory cortices. To investigate this possibility in the somatosensory domain, we measured brain activity using functional magnetic resonance imaging while healthy participants discriminated tactile stimuli in a roving oddball design. Dynamic Causal Modelling revealed that unexpected stimuli increased the strength of forward connections in a caudal to rostral ascending hierarchy from thalamic and somatosensory regions towards insula, cingulate and prefrontal cortices, consistent with hierarchical predictive coding. Within this feed-forward flow of neural coupling, the AIC increased both forwards and backwards connections with prefrontal and somatosensory cortex, supporting a comparator role. Further, we found that greater prefrontal to AIC connectivity predicted subjective ratings of stimulus discrimination difficulty. These results are interpreted in light of embodied predictive coding, suggesting that the AIC coordinates global cortical processing of tactile changes to support body awareness.
This is a preprint of my manuscript investigating AIC connectivity changes during tactile deviancy processing. The paper has been submitted to Social Cognitive and Affective Neuroscience for review.
"Following" is like subscribing to any updates related to a preprint.
These updates will appear in your home dashboard each time you visit PeerJ.
You can also choose to receive updates via daily or weekly email digests.
If you are following multiple preprints then we will send you
no more than one email per day or week based on your preferences.
Note: You are now also subscribed to the subject areas of this preprint
and will receive updates in the daily or weekly email digests if turned on.
You can add specific subject areas through your profile settings.