Consolidation chemotherapy may improve pathological complete response for locally advanced rectal cancer after neoadjuvant chemoradiotherapy: a retrospective study

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Introduction

Materials and Methods

Patients

Treatment strategy

Outcomes

Statistical methods

Results

Patient characteristics

Surgical procedures and pathologic outcome

Safety

Discussion

Conclusions

Supplemental Information

Additional Information and Declarations

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Jin Cui analyzed the data, prepared figures and/or tables, and approved the final draft.

Xue Dou performed the experiments, prepared figures and/or tables, and approved the final draft.

Yanlai Sun conceived and designed the experiments, authored or reviewed drafts of the paper, and approved the final draft.

Jinbo Yue conceived and designed the experiments, performed the experiments, authored or reviewed drafts of the paper, and approved the final draft.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The study was approved by the Institutional Research Ethics Committee of Shandong Cancer Hospital in Jinan, Shandong (#2019-23).

Data Availability

The following information was supplied regarding data availability:

The raw data are available as a Supplemental File.

Funding

This work was supported by the National Nature Science Foundation of China (Grant No. 81871895) and Young Taishan Scholars and Academic Promotion Program of Shandong First Medical University (Grant No. 2019RC003). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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