Association between triglyceride glycemic index and ejection fraction preserved heart failure in hypertensive patients

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Cardiovascular and Metabolic Disorders

Main article text

 

Introduction

Materials and Methods

Study design and participants

Inclusion criteria

Exclusion criteria

General clinical data collection and laboratory test

Echocardiographic evaluation

Diagnosis of heart failure with preserved ejection fraction

Statistical analyses

Results

Baseline characteristics of hypertensive patients grouped by TyG index tertiles

Correlation analysis of TyG index with important cardiac indices in hypertensive patients

Association between TyG index and occurrence of HFpEF in patients with essential hypertension

Predictive power of TyG index for HFpEF

Discussion

Conclusion

Supplemental Information

Additional Information and Declarations

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Xue-Feng Shan conceived and designed the experiments, performed the experiments, prepared figures and/or tables, and approved the final draft.

Long Yang performed the experiments, analyzed the data, prepared figures and/or tables, and approved the final draft.

Xiao-Ming Gao conceived and designed the experiments, authored or reviewed drafts of the article, and approved the final draft.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

This study involving human participants was reviewed and approved by the Ethics Committee of the First Affiliated Hospital of Xinjiang Medical University (approval number: S220722-25). All patients provided written informed consent for their participation in this study.

Data Availability

The following information was supplied regarding data availability:

The raw data is available in the Supplemental File.

Funding

This research was supported by the National Natural Science Foundation of China (U1903212&82360051) and the Key Research and Development Special Program of the Science and Technology Department of Xinjiang Uygur Autonomous Region (2023B03020). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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