Feasibility of using chest computed tomography (CT) imaging at the first lumbar vertebra (L1) level to assess skeletal muscle mass: a retrospective study

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Main article text

 

Introduction

Materials and Methods

Study population

CT scans evaluation

Parameters measurement

Statistical analysis

Results

Baseline characteristics of study population

Association between L1 SMI and sex, age, BMI and BSA

Correlation analysis between L1 and L3 muscle mass measures

The sex-specific cut-off values of L1 SMI for defining low skeletal muscle mass

Discussion

Conclusions

Supplemental Information

Overall population.

DOI: 10.7717/peerj.16652/supp-1

131 study populations with both L1 and L3 data.

DOI: 10.7717/peerj.16652/supp-2

The association between L1 SMI/SMA and L3 SMI/SMA.

A: The association between L1 SMI and L3 SMI. B: The association in men and women, respectively. C: The association between L1 SMA and L3 SMA.D: The association in men and women, respectively. Abbreviations: L1, the first lumbar vertebra; L3, the third lumbar vertebra; SMI, skeletal muscle index.

DOI: 10.7717/peerj.16652/supp-3

Additional Information and Declarations

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Shaohua Liu performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the article, and approved the final draft.

Xia Han performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the article, and approved the final draft.

Jianjun Li analyzed the data, prepared figures and/or tables, and approved the final draft.

Xia Xie analyzed the data, authored or reviewed drafts of the article, and approved the final draft.

Yunkai Yang analyzed the data, authored or reviewed drafts of the article, and approved the final draft.

Wangyan Jiang analyzed the data, authored or reviewed drafts of the article, and approved the final draft.

Li Liu conceived and designed the experiments, prepared figures and/or tables, and approved the final draft.

Zhelong Liu conceived and designed the experiments, authored or reviewed drafts of the article, and approved the final draft.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Ethics Committee of Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology (Ethical Application Ref: TJ-IRB20191201).

Data Availability

The following information was supplied regarding data availability:

The raw measurements are available in the Supplemental Files.

Funding

This work was supported by the Teaching Research Fund of Huazhong University of Science and Technology (No. 2021144 to Zhelong Liu and No. 2022141 to Li Liu) and the Sen-Mei China Diabetes Research Fund (No. Z-2017-26-1902). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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