DPM1 expression as a potential prognostic tumor marker in hepatocellular carcinoma

View article
Bioinformatics and Genomics

Main article text

 

Introduction

Material and Methods

Datasets

UALCAN

Human Protein Atlas

GEPIA

cBioPortal

Metascape

Cell culture

RT-qPCR

Results

Transcriptional levels of DPMS in liver cancer

Relationship between the mRNA levels of DPMS and the clinicopathological parameters in liver cancer patients

Prognostic value of mRNA expression of DPMS in liver cancer patients

DPMS genetic alteration and similar gene network in patients with HCC

Functional enrichment analysis of DPMS in patients with HCC

The mRNA expression levels of DPM1/2/3 in vitro

Discussion

Conclusion

Supplemental Information

Similar genes for DPM1/2/3

DOI: 10.7717/peerj.10307/supp-1

Raw data for RT-qPCR

DOI: 10.7717/peerj.10307/supp-2

Additional Information and Declarations

Competing Interests

The authors declare there are no competing interests.

Author Contributions

Ming Li conceived and designed the experiments, performed the experiments, prepared figures and/or tables, authored or reviewed drafts of the paper, and approved the final draft.

Shengli Xia performed the experiments, analyzed the data, authored or reviewed drafts of the paper, and approved the final draft.

Ping Shi performed the experiments, authored or reviewed drafts of the paper, and approved the final draft.

Data Availability

The following information was supplied regarding data availability:

Raw data are available at TCGA (search term: TCGA LIHC), NCBI GEO (GSE114783, GSE128726 and GSE89632), and in the Supplemental Files.

Funding

This work was sponsored by grants from the National Natural Science Foundation of China (31671309), and the Training Planned Fund of Academic Leaders, Shanghai Pudong New Area Health System (PWR 12018-09). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

8 Citations 1,652 Views 358 Downloads