I pursued my bioinformatics Ph.D. degree in the center of bioinformatics in Peking University. During my Ph.D. study, I received comprehensive training in molecular biology, biostatistics and bioinformatics including research designs, computational tool development and database implementation. With a solid background and comprehensive knowledge in bioinformatics and biological networks, I filled a postdoctoral research fellow position at the Vanderbilt University. During this period, I received excellent training in the understanding of genetics of complex diseases including cancer and pulmonary disease, and I applied my bioinformatics skills in analysis of large scale next-generation sequencing (NGS) data.
To date, I have worked in four different research areas. The first is data collection from public literature and databases to build bioinformatics tools for public use. The second is the integrative analysis of NGS data to decipher the genetic mechanism of complex disease. Thirdly, I applied network-based strategy on the interplay of tumor suppressor genes (TSGs) and oncogenes (OCGs) using the public cancer genomic/epigenetic data. Lastly, I translated my disease genomics expertise to huge marine genomic data to explore the common cell-cell communication mechanisms of metazoan.
Professor emeritus of the University of Freiburg and the University of Heidelberg & the past Scientific Director of the German Cancer Research Center in Heidelberg. Awards include the Robert-Koch-Price; the Charles S. Mott Prize; the Paul-Ehrlich-Ludwig Darmstätter-Price; & the 2008 Nobel-Prize for Medicine. Past Editor in Chief of the International Journal of Cancer and former member of the Board of Directors of the International Union against Cancer (UICC).