Jonathan Arch
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Jonathan RS Arch


I spent 27 years in drug discovery in Beecham and SmithKline Beecham, mainly working on obesity and diabetes. My long-term interest has been in the regulation of energy expenditure, especially by beta3-adrenoceptors. I moved to the Clore Laboratory in 2001, where my recent interests have included short chain fatty acid receptors, the influence of maternal nutrition on susceptibility of offspring to metabolic disease, and ligand-directed (biased) signalling via the beta2-adrenoceptor.

Biochemistry Diabetes & Endocrinology

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Dean of Science and Deputy Director of Metabolic Research

University of Buckingham
Clore Laboratory


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