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Claudiu Supuran
PeerJ Editor, Author & Reviewer
185 Points

Contributions by role

Author 135
Reviewer 50

Contributions by subject area

Biochemistry
Bioinformatics
Evolutionary Studies
Biophysics
Drugs and Devices
Microbiology
Infectious Diseases

Claudiu T. Supuran

PeerJ Editor, Author & Reviewer

Summary

Claudiu T. Supuran is professor of medicinal and pharmaceutical chemistry at the University of Florence, Italy, since 1995. He did his Ph D at University of Bucharest, Romania, and was a visiting scholar at University of Florida, Gainesville, USA, and at Grifitth University, Brisbane, Australia. He was visiting professor at University of La Plata, Argentina and at University of New South Wales, Sydney, Australia. His main research interest is the medicinal chemistry/biochemistry of carbonic anhydrases, field in which he has made contributions to the design of many novel classes of enzyme inhibitors and activators, deciphering their mechanism of action at molecular level, discovery of new isoforms and their role in disease (cancer, obesity, epilepsy, neuropathic pain and cognition), discovery and characterization of carbonic anhydrases from various organisms (bacteria, fungi, corals, vertebrates other than humans and rodents, etc). Other research interests include X-ray crystallography of metallo-enzymes, heterocyclic chemistry, chemistry of sulfonamides, metal-based drugs, cyclooxygenases, serine proteases, matrix metalloproteinases, bacterial proteases, and amino acid derivatives among others. He has published more than 1500 papers in these fields and his Hirsch index is 134. One of the compounds discovered in his laboratory (SLC-0111) is in Phase II clinical trials for the treatment of advanced metastatic solid tumors

Biochemistry Bioorganic Chemistry Biophysical Chemistry Biophysics Drugs & Devices Obesity

Editing Journals

PeerJ Organic Chemistry
PeerJ Inorganic Chemistry
PeerJ Analytical Chemistry

Past or current institution affiliations

University of Florence

Work details

Professor of Medicinal Chemistry

University of Florence
March 1995
NEUROFARBA
Teaching duty: Pharmaceutical Chemistry II

Websites

  • Google Scholar

PeerJ Contributions

  • Articles 1
  • Reviewed 1
December 7, 2017
Identification and characterization of a novel zebrafish (Danio rerio) pentraxin–carbonic anhydrase
Maarit S. Patrikainen, Martti E.E. Tolvanen, Ashok Aspatwar, Harlan R. Barker, Csaba Ortutay, Janne Jänis, Mikko Laitaoja, Vesa P. Hytönen, Latifeh Azizi, Prajwol Manandhar, Edit Jáger, Daniela Vullo, Sampo Kukkurainen, Mika Hilvo, Claudiu T. Supuran, Seppo Parkkila
https://doi.org/10.7717/peerj.4128 PubMed 29230365

Signed reviews submitted for articles published in PeerJ Note that some articles may not have the review itself made public unless authors have made them open as well.

March 30, 2021
In vitro and in vivo activities of the carbonic anhydrase inhibitor, dorzolamide, against vancomycin-resistant enterococci
Nader S. Abutaleb, Ahmed E.M. Elhassanny, Daniel P. Flaherty, Mohamed N. Seleem
https://doi.org/10.7717/peerj.11059 PubMed 33850651