31 October 2022

A Python script to design primers for overlap extension PCR to ligate two DNA fragments

"The use of simple tools for designing primers to generate overlapping PCR fragments is so useful for any laboratory using molecular tools. This open source script is easy and helpful in this tasks."

Bernardo Franco, Handling Editor

25 October 2022

2FAST2Q: a general-purpose sequence search and counting program for FASTQ files

"Bravo and colleagues present 2FAST2Q, a tool help both biologists and bioinformaticians quickly interpret certain short-read amplicon sequencing analyses, e.g., CRISPRi-Seq, Tn-Seq, and RB-Seq. It can also act as a general-purpose sequence search and counting program for FASTQ files."

Joseph Gillespie, Handling Editor

13 October 2022

Ribovirus classification by a polymerase barcode sequence

"It may help in the discovery of new riboviruses and will hopefully have an impact on metagenomic studies. Therefore this work will be of great interest not only to virologists but to a wide range of researchers dealing with viruses, from environmental biologists to clinicians."

Ana Grande-Pérez, Handling Editor

23 September 2022

Utilizing network pharmacology and experimental validation to investigate the underlying mechanism of phellodendrine on inflammation

"A case study on the bioactive molecule phellodendrine and its role in mitigating inflammation"

Srinivas Sistla, Handling Editor

23 September 2022

16S-FASAS: an integrated pipeline for synthetic full-length 16S rRNA gene sequencing data analysis

"This pipeline should help those investigating full length SSU sequences."

Craig Moyer, Handling Editor

15 August 2022

Neighborhood-based inference and restricted Boltzmann machine for microbe and drug associations prediction

"The report presented here presents a promising method for the discovery of novel drugs with antimicrobial activity."

Bernardo Franco, Handling Editor

5 August 2022

Skimming for barcodes: rapid production of mitochondrial genome and nuclear ribosomal repeat reference markers through shallow shotgun sequencing

"This study shows that genome skimming is an efficient and cost effective method that will allow a shift in the DNA barcoding workflow from sequencing targeted loci in individual specimens to generating complete suites of barcode markers for many taxa in a single sequencing run."

Xavier Pochon, Handling Editor

11 July 2022

Tucuxi-BLAST: Enabling fast and accurate record linkage of large-scale health-related administrative databases through a DNA-encoded approach

"New a pplication of BLAST"

Maria Cristina Albertini, Handling Editor

27 June 2022

Therapeutic targets and signaling pathways of active components of QiLing decoction against castration-resistant prostate cancer based on network pharmacology

"this work may have a potential in overcoming the problem of castrate resistant prostate cancer."

Ferdinand Frauscher, Handling Editor

14 June 2022

AntiDMPpred: a web service for identifying anti-diabetic peptides

"This paper outlines a new tool to help scientists identify and explore anti-diabetic peptides using machine learning methods. There is a really nice user-interface and is one a kind in this space. his has potential to be developed into other areas beyond diabetes research."

Gwyn Gould, Handling Editor