16 August 2023

Detection of single nucleotide polymorphisms in virus genomes assembled from high-throughput sequencing data: large-scale performance testing of sequence analysis strategies

"Detection of virus variants is important in many fields, including human health. The lessons learned here can translate to other viruses in different systems."

Brenda Oppert, Section Editor

14 August 2023

Tailored modulation of S100A1 and RASSF8 expression by butanediamide augments healing of rotator cuff tears

"Conducive to clinical diagnosis and treatment"

Yuzhen Xu, Handling Editor

9 August 2023

EDIL3 is a potential prognostic biomarker that correlates with immune infiltrates in gastric cancer

"for Gastric Cancer, there is no specific diagnostic/prognostic marker is available to date. EDIL3 in a larger cohort may be useful for the Gastric cancer patients."

Girijesh Patel, Handling Editor

21 July 2023

Protein family neighborhood analyzer—ProFaNA

"Baranowski and Pawłowski provide a valuable tool for bioinformatics analysis of linked genes. This is an under-appreciated approach to assigning putative functions of hypothetical genes and proteins to common neighbors across different genomes. There aren't many easy approached for this method."

Joseph Gillespie, Handling Editor

17 July 2023

Review of feature selection approaches based on grouping of features

"This work surveyed different methods for feature selection using feature grouping (i.e., crucial to choose the most relevant features in high-dimensional datasets). This review will be helpful for people working in different disciplines (especially researchers working in large-scale omics data integration)."

Reema Singh, Handling Editor

17 July 2023

Comparative analysis of automatic segmentation of esophageal cancer using 3D Res-UNet on conventional and 40-keV virtual mono-energetic CT Images: a retrospective study

"This study revealed that fully automated segmentation of esophageal cancer with 3D Res-UNet has high accuracy and clinically feasibility."

Feng Liu, Handling Editor

5 July 2023

Development of a circHIPK3-based ceRNA network and identification of mRNA signature in breast cancer patients harboring BRCA mutation

"This study has deepened our understanding of the molecular mechanisms of breast cancer."

Peixin Dong, Handling Editor

26 June 2023

Multi-Object Tracking in Heterogeneous environments (MOTHe) for animal video recordings

"MOTHe is a promising improvement to track movement of animals, demonstrated with a small wasp and larger antelope, and has training to improve detection."

Brenda Oppert, Section Editor

5 June 2023

Ferroptosis-associated gene CISD2 suppresses colon cancer development by regulating tumor immune microenvironment

"The study on the prognostic value of CISD2 in colorectal adenocarcinoma will be helpful for clinical prevention and treatment."

Yuzhen Xu, Handling Editor

11 May 2023

The effect of FMT and vitamin C on immunity-related genes in antibiotic-induced dysbiosis in mice

"More studies are needed to investigate the efficacy of antibiotics in dysbiosis."

Mehmet Burak Ateş, Handling Editor