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Supplemental Information

Additional Information

Competing Interests

The authors declare they have no competing interests.

Author Contributions

Nikolay Natchev conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Nikolay Tzankov analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Ingmar Werneburg analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Egon Heiss conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The animals were obtained commercially. As no invasive techniques were applied, no approval documents were needed during the time of the experiments, according to Austria's regulations.

Data Deposition

The following information was supplied regarding the deposition of related data:

figshare.com/s/5d9e23c8f4ec11e49cb306ec4b8d1f61 - figshare.com/s/1920fc6af4ed11e4972106ec4bbcf141

Funding

The study was funded by FWF Austrian Science Fund, Project no. P20094-B17 on that E.H. and N.N. were employed and the Advanced Postdoc Mobility fund P300P3_158526 of the Swiss National Science Foundation granted to I.W. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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