Orexin A exerts more thermogenic than orexinergic functions
- Published
- Accepted
- Subject Areas
- Neuroscience, Anatomy and Physiology
- Keywords
- eating behavior, sympathetic nervous system, thermoregulation
- Copyright
- © 2014 Messina et al.
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ PrePrints) and either DOI or URL of the article must be cited.
- Cite this article
- 2014. Orexin A exerts more thermogenic than orexinergic functions. PeerJ PrePrints 2:e392v1 https://doi.org/10.7287/peerj.preprints.392v1
Abstract
In this article we focus on the role of orexin A in the thermoregulatory functions and its link to food intake. This peptide is named orexin A to emphasize the increase in food intake due to this peptide. The influence of eating behavior could be only secondary to change in the thermoregulatory set-point to reach a determined core temperature. Our viewpoint is compared with vision of other authors, finding possible concordance and disagreement. Activity of the sympathetic nerves system, brown adipose tissue and central body temperatures, heart rate and food intake were monitored to measure the modifications induced by an intracerebroventricular injection of orexin A on the thermoregulation and eating behavior in various experimental conditions.
Author Comment
The manuscript will be submitted to another journal.