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Additional Information

Competing Interests

The authors of this paper have no competing interests.

Author Contributions

Gabrielle E Brown conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Leslie S. Ritter contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Paul F. McDonagh contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Zoe Cohen conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

University of Arizona Animal Care and Use Committee, under Protocol 08-105 (Novel Use of a Natural Product for Acute Stroke Therapy)

Funding

This work was supported by the funds of the Sarver Heart Center: The Philip and Bobby Hanft Young Investigator Award (Z. Cohen). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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