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Supplemental Information

Additional Information

Competing Interests

John M Carroll is an Academic Editor for PeerJ Computer Science.

Author Contributions

Yu Wu conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, performed the computation work, reviewed drafts of the paper.

Na Wang conceived and designed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, performed the computation work, reviewed drafts of the paper.

Jessica Kropczynski conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper, suggested alternative directions as well as literatures..

John M Carroll conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper, oversaw the entire process..

Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Penn State University Institutional Review Board

Funding

The authors received no funding for this work.


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