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Additional Information

Competing Interests

No competing financial interests exist.

Author Contributions

Peter B Chi analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Andrea Duncan conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Patricia Ann Kramer conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Vladimir Minin contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Grant Disclosures

The following grant information was disclosed by the authors:

National Scientific Foundation grant DMS 0856099,

National Institutes of Health grant IRC4AI092828-01,

National Institutes of Health grant U01 AG21379.

Funding

VNM was supported by the National Scientific Foundation grant DMS 0856099 and National Institutes of Health grant IRC4AI092828-01. PAK was supported by the National Institutes of Health grant U01 AG21379. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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