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Important metabolites in maintaining folic acid, homocysteine and polyamine metabolism associated with ranibizumab treatment in cultured Human Tenon’s Fibroblast

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151 days ago
Important metabolites in maintaining folic acid, homocysteine and polyamine metabolism associated with ranibizumab treatment in cultured Human Tenon’s Fibroblast https://t.co/9xkFzAJiTO https://t.co/fOawBEapVL
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Supplemental Information

Up-regulated and down-regulated metabolite in ranibizumab treated-HTFs group and control HTFs group

DOI: 10.7287/peerj.preprints.27492v1/supp-1

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Siti Munirah Md Noh conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Siti Hamimah Sheikh Abdul Kadir conceived and designed the experiments, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Sushil Kumar Vasudevan conceived and designed the experiments, authored or reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

1. University Teknologi MARA Ethics Committee Board granted Ethical Approval to carry out the study within facilities (600-RMI (5/1/6))

2. National Medical Research Register (NMRR) granted Ethical Approval to carry out the study within facilities (Research ID:10601)

Data Deposition

The following information was supplied regarding data availability:

The raw data is provided in the supplementary file 3. The data shows all the significant results from both ranibizumab-treated HTFs group and control groups.

Funding

This work was supported by The Ministry of Science, Technology and Innovation (MOSTI), Malaysia. Project Code: 100-RMI/SF/16/6/2 The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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