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Additional Information

Competing Interests

None of the authors declare any competing interest

Author Contributions

Sarah Gray conceived and designed the experiments, wrote the paper.

Steven Woltering conceived and designed the experiments, performed the experiments, analyzed the data.

Karizma Mawjee performed the experiments.

Rosemary Tannock conceived and designed the experiments, wrote the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The present study was approved by the institutional Research Ethics Board (protocol reference #23977) and all participants provided informed written consent prior to the start of the study.

Funding

Funding for this project was provided by the Canadian Institute for Health Research (Tannock & Lewis; #482246) and the Canada Research Chair Program (RT). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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