A Gauge model-based analysis of: Reduction(s) in osmolyte infusion interval and its effects on the aggregate measure of systemic failure for a unicellular system
- Published
- Accepted
- Subject Areas
- Biochemistry, Bioengineering, Biophysics, Cell Biology, Mathematical Biology
- Keywords
- Osmolyte infusion, Infusion interval, High output functional response, Systemic failure
- Copyright
- © 2015 Jeff-Eke
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ PrePrints) and either DOI or URL of the article must be cited.
- Cite this article
- 2015. A Gauge model-based analysis of: Reduction(s) in osmolyte infusion interval and its effects on the aggregate measure of systemic failure for a unicellular system. PeerJ PrePrints 3:e1163v2 https://doi.org/10.7287/peerj.preprints.1163v2
Abstract
This is a companion to A Gauge model for analysis of Biological systems. Here we reconcile the gauge model with a “real” system, which in this case is a unicellular system. We address effects of infusion of free osmolytes into an intracellular space of interest, and how changes to the frequency of infusion affects the aggregate measure of systemic failure. We also describe limitations to the functionality of the system that may stem from a limited availability of resources. We end by introducing a theoretical problem related to how well the system can tolerate random and extreme changes to the frequency of osmolytes presented via infusion.
Author Comment
This is a revised version of the paper.
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