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Current Issue - October 2025

Table of Contents - PeerJ (Medicine Articles)

October 31, 2025

NAT10 inhibits ferroptosis and promotes the progression of renal clear cell carcinoma by regulating the NFE2L1-GPX4 signaling pathway

Chao Tan, Yang Wang, XinJie Zhang, ZiKang Li, Shubo Chen

https://doi.org/10.7717/peerj.20224 PubMed 41189569

October 29, 2025

Identification and experimental verification of necroptosis-related prognostic gene signature and characterization of tumor immune infiltration in lung squamous cell carcinoma

Kai Sun, Ke-run Wang, Song Wen, Juan-juan Hong, Yu-lang Fei, Qing-hua Pan, Fang-fang Xie

https://doi.org/10.7717/peerj.20260 PubMed 41180485

October 29, 2025

Effects of virtual reality exercise on fatigue, pain, and psychological status among cancer patients: a meta-analysis

Ruihan Wang, Yunwei Wang, Shiming Li, Shuoqi Li

https://doi.org/10.7717/peerj.20196 PubMed 41180479

October 28, 2025

Comparison of the clinical usefulness of CXCL-8 and common clinical tumor markers for esophageal cancer diagnosis

Pingxia Lu, Baowei Xu, Xinyu Zhang, Cuifeng Zheng, Xianqiang Chen, Junrong Zhang, Yingping Cao, Zhengyuan Huang

https://doi.org/10.7717/peerj.20079 PubMed 41180488

October 27, 2025

Retrospective study: the value of GDF-15 and conventional markers in combination for clinical diagnosis of lung cancer

Jingru Ni, Xiaohe Hao, Yongkang Wu, Cuiping Mao, Limin Niu, Heng Liu, Qinghai Lin

https://doi.org/10.7717/peerj.20281 PubMed 41180487

October 24, 2025

The expression of metastasis associated protein 2 in normal development and cancers: mechanism and clinical significance

Xujun Liu, Yaping Jiang, Yanfeng Hou, Xiaoning Li, Haixia Li, Wenzhe Si

https://doi.org/10.7717/peerj.20107 PubMed 41159000

October 21, 2025

Integrative bioinformatics analysis identifies C1orf198 as a novel prognostic biomarker in colorectal cancer

Changjiang Yang, Xuhua Geng, Zihan Zhao

https://doi.org/10.7717/peerj.20227 PubMed 41142306

October 20, 2025

Mendelian randomization and nomogram-based prediction of hepatocellular carcinoma risk in patients with hepatitis B cirrhosis

Xiaolong Zheng, Yiping Hong, Wei Wei

https://doi.org/10.7717/peerj.20179 PubMed 41142312

October 14, 2025

Prediction of pathological complete response to neoadjuvant chemotherapy for invasive breast cancers based on longitudinal ultrasound and superb microvascular imaging: a single-center retrospective study

Yanling Zuo, Yongtao Zhan, Jie Zhou, Haoming Xia, Tao Li, Fan Zhou, Chunyue Luo, Huafeng Zeng, Yingjia Li

https://doi.org/10.7717/peerj.20171 PubMed 41112760

October 8, 2025

Evaluation of NEUROG1 methylation status in stool specimens in the advanced adenomas and colorectal cancer

Lijin Zhang, Aiping Lin, Jie Lin, Juan Chen, Mengshi Chen, Xunbin Yu, Yijuan Wu, Tao Wang, Yan Lu, Zhaofen Ba, Xiaowei Cheng, Tiantian Zhang, Minghong Chen

https://doi.org/10.7717/peerj.19968 PubMed 41081101

October 6, 2025

Predictive role of systemic immune-inflammation index in the prognosis of patients with advanced left-sided colorectal cancer: a retrospective study

Jingyue Su, Shaokun Yu, Yanjie Xu, Jiemin Zhao, Wenwei Hu, Xuefeng Ni

https://doi.org/10.7717/peerj.20095 PubMed 41081107

October 6, 2025

NT-proBNP serves as a prognostic marker for adverse outcomes in severe immune checkpoint inhibitor-associated myocarditis

Cheng He, Linjuan Xu, Zhihong Zhang, Jiong Wang

https://doi.org/10.7717/peerj.20020 PubMed 41081106

October 6, 2025

Oropharyngeal microbiome dysbiosis in esophageal squamous cell carcinoma: taxonomic shifts, metabolic reprogramming, and geographic disparities in a high-incidence cohort

Ying Liu, Erman Wu, Fang Cheng, Meng Zhang, Qian Rou, Zinati Nuertai, Maorong Xu, Shanshan Xu, Minghui Li, Lei Zhang, Aheli Nasiroula

https://doi.org/10.7717/peerj.20009 PubMed 41081109

October 6, 2025

The 12-LOX/12-HETE/GPR31 metabolic pathway promotes tumor-associated macrophage M2 polarization mediated pancreatic cancer development

Ying Yang, Yuanzhen Wang, Jia Wu, Chunxiu Tan, Liya Huang

https://doi.org/10.7717/peerj.19963 PubMed 41081084

October 3, 2025

The BAF53A-BACH1-GCLM axis regulates glutathione metabolism and enhances ferroptosis resistance in esophageal squamous cell carcinoma

Weijuan Jiang, Jie Zhang, Canjuan Chen, Jiangwei Shi, Lihua Fan

https://doi.org/10.7717/peerj.20156 PubMed 41059410

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