Biology & Life sciences - Table of Contents

September 28, 2022

BRCA1 overexpression attenuates breast cancer cell growth and migration by regulating the pyruvate kinase M2-mediated Warburg effect via the PI3K/AKT signaling pathway

Xiuli Liu, Hanxu Liu, Lei Zeng, Yuetao Lv

https://doi.org/10.7717/peerj.14052 PubMed 36193432

September 28, 2022

Ac2-26 attenuates hepatic ischemia-reperfusion injury in mice via regulating IL-22/IL-22R1/STAT3 signaling

Wanzhen Li, Hongxin Jiang, Chen Bai, Shuna Yu, Yitong Pan, Chenchen Wang, Huiting Li, Ming Li, Yaxin Sheng, Fangfang Chu, Jie Wang, Yuting Chen, Jianguo Li, Jiying Jiang

https://doi.org/10.7717/peerj.14086 PubMed 36193422

September 23, 2022

Utilizing network pharmacology and experimental validation to investigate the underlying mechanism of phellodendrine on inflammation

Lili Hu, Jue Wang, Na Wu, Xiaoge Zhao, Donghui Cai

https://doi.org/10.7717/peerj.13852 PubMed 36172495

September 21, 2022

DDX17 modulates the expression and alternative splicing of genes involved in apoptosis and proliferation in lung adenocarcinoma cells

Cheng He, Gan Zhang, Yanhong Lu, Jingyue Zhou, Zixue Ren

https://doi.org/10.7717/peerj.13895 PubMed 36164607

September 21, 2022

IRF7-deficient MDCK cell based on CRISPR/Cas9 technology for enhancing influenza virus replication and improving vaccine production

Oraphan Mayuramart, Witthaya Poomipak, Somruthai Rattanaburi, Kritsada Khongnomnan, Songtham Anuntakarun, Suthat Saengchoowong, Tanit Chavalit, Naphat Chantaravisoot, Sunchai Payungporn

https://doi.org/10.7717/peerj.13989 PubMed 36164603

September 16, 2022

Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer

Min Weng, Chenghao Shi, Hui Han, Hengyue Zhu, Yanyi Xiao, Hangcheng Guo, Zhixian Yu, Cunzao Wu

https://doi.org/10.7717/peerj.14042 PubMed 36132221

September 13, 2022

Moonlighting proteins in medically relevant fungi

Verania J. Arvizu-Rubio, Laura C. García-Carnero, Héctor Manuel Mora-Montes

https://doi.org/10.7717/peerj.14001 PubMed 36117533

September 2, 2022

Bone mesenchymal stem cell-derived exosomes prevent hyperoxia-induced apoptosis of primary type II alveolar epithelial cells in vitro

Wei Yang, Chao Huang, Wenjian Wang, Baozhu Zhang, Yunbin Chen, Xinlin Xie