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Reema Singh
Summary
I am a computational Biologist/Bioinformatician with more than 14 years of research experience. I obtained my Master's and Ph.D. degrees in “Bioinformatics” from Chaudhary Charan Singh Haryana Agricultural University (Hisar, India) in 2006 and Jawaharlal Nehru University (JNU, New Delhi, India) in 2015, respectively. I worked as Scientist-1 in the “Biomedical Informatics center” at the Indian Council of Medical Research (New Delhi, India) from 2006 to 2012. During my stay in ICMR, I developed an antimicrobial resistance (AMR) gene database of ß-lactamase proteins (Dlact) from 814 publically available bacterial genomes. This database contains 2020 ß-lactamases which were further classified using graph-based clustering of best bidirectional hits to identify the group-specific signature of ß-lactamases.
I moved to Scotland (United Kingdom) in 2013 for my first postdoc in Bioinformatics at the University of Dundee. In my first postdoc, I performed the bioinformatics analysis of next-generation data generated from various projects related to the model organism Dictyostelium discoideum (which aims to probe the genetic pathways involved in different stages of development). In 2017, I joined the university of Saskatchewan for a second postdoc to work on a research project entitled “A Disruptive Whole Genome Sequencing Platform for the Simultaneous Identification and Characterization of Multiple Sexually Transmitted Pathogens”. As a part of the project, I have developed a computational Whole Genome Sequencing (WGS) pipeline, named Gen2Epi, to link full genomes to antimicrobial susceptibility and molecular epidemiological data in Neisseria gonorrhoeae. In my current position (since March 2022) as Bioinformatician and Data Manager at the Vaccine and Infectious Disease Organization, I am applying my bioinformatics skills to understand host response to viral infections.
Artificial Intelligence Bioinformatics Computational Biology Data Mining & Machine Learning Databases Genomics Infectious Diseases Omics Technologies