Bioinformatics and Genomics

Finding novel relationships with integrated gene-gene association network analysis of Synechocystis sp. PCC 6803 using species-independent text-mining

Editor rating: 9 / 10

Hugo Sarmento –– Litterature text-mining to discover gene-gene interaction.
PlasmidSeeker: identification of known plasmids from bacterial whole genome sequencing reads

Section Editor rating: 8 / 10

Elena Papaleo –– The authors present a novel tool, PlasmidSeeker, which could be useful for genomic research and also help the time-consuming and tedious assembly steps.
Out of Asia: mitochondrial evolutionary history of the globally introduced supralittoral isopod Ligia exotica

Editor rating: 8 / 10

Curtis Daehler –– This work provides genetic evidence suggesting the native range of a widely distributed animal that was accidentally spread by humans starting hundreds of years ago.
The little shrimp that could: phylogeography of the circumtropical Stenopus hispidus (Crustacea: Decapoda), reveals divergent Atlantic and Pacific lineages

Editor rating: 8 / 10

Xavier Pochon –– This study provides the first range-wide phylogeographic study of the banded coral shrimp S. hispidus, extending across more than 27,000 km of the globe. Coalescence analysis brings evidence that an isolated Indo-Pacific lineage evolved from a rare dispersal event from the Atlantic around South Africa via the Benguela Current, thereby colonizing the Indian and Pacific Oceans, followed by dispersal across the Indo-Pacific in the last 200,000 years. Surprisingly, this benthic coral reef associated shrimp shows a single haplotype dominating the largest continuous tropical oceanic expanse on the planet.
A simple molecular technique for distinguishing species reveals frequent misidentification of Hawaiian corals in the genus Pocillopora

Editor rating: 8 / 10

Xavier Pochon –– This study developed a simple and cost-effective assay that quickly allows for discrimination amongst coral species in the genus Pocillopora using simple PCR amplification followed by digestion with widely available restriction enzymes. Pocilloporid corals exhibit extreme phenotypic plasticity, making morphological identification of species very challenging. The assay was tested on 691 coral samples collected from across the Hawaiian Archipelago and successfully characterised all six Pocillopora species occurring in Hawaii. Compared to sequence-based identification, this method is simple, rapid and represents a cost saving of nearly 95%. This work will benefit future studies of population structure, ecology, biodiversity, evolution and conservation in this challenging coral genus.
Complex versus simple models: ion-channel cardiac toxicity prediction

Editor rating: 8 / 10

Heiko Enderling –– This article discusses the contributions of quantitative models in predicting biology, and makes an important point about the balance of simplicity/complexity/accuracy/usefulness of biophysical models. If simple models capture biological complexity, the use of more detailed models must be properly justified.
Evaluating the adaptive evolutionary convergence of carnivorous plant taxa through functional genomics

Editor rating: 8 / 10

Todd Vision –– This is a novel and innovative approach to studying the genomic correlates of convergent evolution. It is likely to inspire similar studies in other systems and for other kinds of genomic changes, as well as bioinformatic work to refine and extend the methods.
Translating genomics into practice for real-time surveillance and response to carbapenemase-producing Enterobacteriaceae: evidence from a complex multi-institutional KPC outbreak

Editor rating: 9 / 10

Nicholas Loman –– This is a really well worked example of how whole genome sequencing is transforming public health surveillance of infectious diseases.
Genome-wide identification of ABA receptor PYL family and expression analysis of PYLs in response to ABA and osmotic stress in Gossypium

Editor rating: 10 / 10

Pankaj Jaiswal –– It contributes to PYL gene family annotation in cotton.
A microbial survey of the International Space Station (ISS)

Editor rating: 9 / 10

Joël Mossong –– This is an interesting article on the microbial contamination of an unusual habitat in space, the international space station.

Discussing these articles

Well done Sanna, Suwisa and Filip

PlasmidSeeker: identification of known plasmids from bacterial whole genome sequencing reads https://t.co/ltYMfY300w via @thePeerJ

The little shrimp that could: phylogeography of the circumtropical Stenopus hispidus (Crustacea: Decapoda), reveals divergent Atlantic and Pacific lineages https://t.co/TXOB7dyxro https://t.co/QkZN9Zfxz0

New paper to ID Pocillopora corals https://t.co/It92AVvX7X

new publication: https://t.co/MONo6omrX3 a comprehensive analysis on how a well-defined simple heuristic is as good (if not better) than complex mathematical models, used by FDA and bloated pharma companies, in ion-channel safety pharmacology #mathbiology

117 days ago
Evaluating the adaptive evolutionary convergence of carnivorous plant taxa through functional genomics https://t.co/z1sFqYaSeP

145 days ago
Our paper on WGS to inform the public health response to a complex state-wide KPC outbreak in @thePeerJ https://t.co/AGHHHEJcCz with @BenjaminHowden @tstinear @torstenseemann and many others

A microbial survey of the ISS. https://t.co/DMdgTYuwLi via @thePeerJ

Popular Science: "Scientists are trying to figure out which bacteria have colonized our space station"
https://www.popsci.com/ISS-microbiome

The space station is about as sanitary as your run-of-the-mill bachelor pad
https://www.digitaltrends.com/cool-tech/space-station-is-chock-full-of-germs/

The International Space Station is super germy
https://www.washingtonpost.com/news/speaking-of-science/wp/2017/12/05/the-international-space-station-is-super-germy/

The International Space Station is swarming with bacteria
https://cosmosmagazine.com/biology/the-international-space-station-is-swarming-with-bacteria

Just Like Home: Space Station Has Same Microbes As Your House
https://www.space.com/38980-space-station-bacteria-similar-human-homes-study.html

The ISS Bacterial Community Resembles What You'd Find in Your Home
https://www.seeker.com/space/the-iss-bacterial-community-resembles-what-youd-find-in-your-home

International Space Station colonised by mysterious bugs – including ‘alien’ bacteria
http://metro.co.uk/2017/12/05/international-space-station-colonised-mysterious-bugs-including-alien-bacteria-7134669/

'Diverse' bacteria found on International Space Station like that on Earth, scientists reveal
http://www.independent.co.uk/news/science/nasa-international-space-station-bacteria-found-earth-home-humans-study-iss-a8092756.html

The bacterial community on the International Space Station resembles homes
https://phys.org/news/2017-12-bacterial-international-space-station-resembles.html

BACTERIA IN SPACE: INTERNATIONAL SPACE STATION HAS LOTS OF THE SAME MICROBES AS ANY OTHER HOME
http://www.newsweek.com/bacteria-space-international-space-station-has-same-microbes-any-other-home-735208