Editor rating: 7 / 10Keith Crandall –– This paper demonstrates that there is significant hidden diversity still to be discovered and described in this interesting group of Australian freshwater crayfish.
Editor rating: 7 / 10Keith Crandall –– This study presents a novel bioinformatics pipeline for emm gene typing from whole genome sequence data from Streptococcus, the most common etiological agent of throat infections.
Editor rating: 9 / 10Gian Tartaglia –– The identification if CRISPR arrays is crucial to understand how the system works and can be manipulated in applications
Editor rating: 8 / 10Gerrit Beemster –– The approach integrates a large amount of data on flowering time regulation and provides a new method for this incorporating modelling with expression and phenotypic data.
Editor rating: 8 / 10Ana Grande-Pérez –– A comprehensive and useful tool that will aid plant science community in the study of geminivirus genomics
Editor rating: 8 / 10Vladimir Uversky –– Interesting and important data are provided on the peculiarities and mechanisms of fumarate accumulation in Rhizopus delemar ATCC 20344
Editor rating: 8 / 10Walter de Azevedo Jr. –– Drug repositioning is a hot topic in drug development and application of computational tools to improve the chances of success of this methodology is of great interest for a broad spectrum of researchers. The present manuscript reports an interesting analysis of drug repositioning using data from randomized clinical trials available at clinicaltrials.gov. The authors used text mining tools to extract serious adverse event data and their results indicate new uses of existing drugs. In my view, the most important contribution of the present work is the method itself, which could be used for drug repositioning not only for cancer but also for other diseases.
Editor rating: 7 / 10Philip Cox –– Because, although the focus of the article is one particular bone in one species of mammal, the results have implications for understanding the biomechanics of bones much more widely.
Editor rating: 7 / 10Vsevolod Makeev –– It contains a valuable know-how, the important part of bioinformatics practice that is seldom become explained in detail in publications.
Editor rating: 8 / 10Ugo Bastolla –– I think that the new method will make a useful contribution in the fast developing field of microbiota analysis
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