Editor rating: 8 / 10Vladimir Uversky –– Interesting and important data are provided on the peculiarities and mechanisms of fumarate accumulation in Rhizopus delemar ATCC 20344
Editor rating: 8 / 10Walter de Azevedo Jr. –– Drug repositioning is a hot topic in drug development and application of computational tools to improve the chances of success of this methodology is of great interest for a broad spectrum of researchers. The present manuscript reports an interesting analysis of drug repositioning using data from randomized clinical trials available at clinicaltrials.gov. The authors used text mining tools to extract serious adverse event data and their results indicate new uses of existing drugs. In my view, the most important contribution of the present work is the method itself, which could be used for drug repositioning not only for cancer but also for other diseases.
Editor rating: 7 / 10Philip Cox –– Because, although the focus of the article is one particular bone in one species of mammal, the results have implications for understanding the biomechanics of bones much more widely.
Editor rating: 7 / 10Vsevolod Makeev –– It contains a valuable know-how, the important part of bioinformatics practice that is seldom become explained in detail in publications.
Editor rating: 8 / 10Ugo Bastolla –– I think that the new method will make a useful contribution in the fast developing field of microbiota analysis
Editor rating: 8 / 10Tomas Perez-Acle –– A parsimoniously executed research and well written article about transcriptomic studies on T. cruzi that may shed lights on novel targets for the treatment of the chronic disease produced by this parasite.
Editor rating: 7 / 10Stephen Wratten –– vital work on amphibian movement dynamics
Editor rating: 8 / 10D. Gareth Evans –– Panel tests are becoming the bespoke test for cancer predisposition
Editor rating: 8 / 10Valeria Souza –– Streptomyces is a very interesting genera with wide metabolic capabilities, the genome is a confirmation of this interesting metabolism
Editor rating: 7 / 10Yonghong Peng –– Interesting work.
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