Bioinformatics and Genomics

Studying the impact of young age on prognosis and treatment in laryngeal squamous cell carcinomas using the SEER database
Cheng Zhan –– Young patients usually have a different pattern of prognosis compared with old ones.
SLCV–a supervised learning—computer vision combined strategy for automated muscle fibre detection in cross-sectional images
Henkjan Huisman –– The method described in this paper will help advance the scientific analysis of cross-sectional muscular histopathology.
Construction and integrated analysis of crosstalking ceRNAs networks in laryngeal squamous cell carcinoma
Cheng Zhan –– The authors constructed a crosstalking ceRNAs networks in laryngeal squamous cell carcinoma
Evolutionary couplings detect side-chain interactions
Elena Papaleo –– A nice study on the predictive power of sequence-based contact prediction, highlight that evolutionary coupling-based analyses are more prone to identify structural contacts mediated by side-chain atoms than by backbone atom.
An artificial-vision- and statistical-learning-based method for studying the biodegradation of type I collagen scaffolds in bone regeneration systems
Yong Wang –– This work proposes a new method for studying the biodegradation of type I collagen scaffolds in bone regeneration systems.
Molecular mechanisms linking peri-implantitis and type 2 diabetes mellitus revealed by transcriptomic analysis
Cheng-Chia Yu –– IL-6, NFKB1, and PIK3CG expression along with the IL-17 signaling pathway as top candidate molecular linkage mechanisms between periimplantitis and type 2 diabetes mellitus.
Diagnostic performance of clinical properties and conventional magnetic resonance imaging for determining the IDH1 mutation status in glioblastoma: a retrospective study
Cheng-Chia Yu –– The combined use of patient age and tumor volume can enhance the diagnostic specificity of glioblastoma.
Global transcriptomic analysis identifies SERPINE1 as a prognostic biomarker associated with epithelial-to-mesenchymal transition in gastric cancer
Obul Bandapalli –– The authors have shown that SERPINE1 is a potent biomarker associated with EMT and a poor prognosis in GC and FN1, TIMP1, MMP2, and SPARC are correlated with SERPINE1 and may serve as therapeutic targets in reversing EMT in GC.
Identification of microRNA signatures in umbilical cord blood associated with maternal characteristics
Cheng-Chia Yu –– UCB miRNAs should be studied also as biomarkers for screening and diagnosis of 213 pregnancy-associated complications and pathologies.
Identify CRNDE and LINC00152 as the key lncRNAs in age-related degeneration of articular cartilage through comprehensive and integrative analysis
Ugo Bastolla –– This paper identified long coding RNAs that are likely to play an important role in osteoarthritis
Bioinformatics and Genomics

Section discussions

Non-parallel changes in songbird migration timing are not explained by changes in stopover duration @thePeerJ

My take on the cooperative-breeding lifespan question in mammals is out today in @thePeerJ #Ecology #EvolutionaryStudies "The case for extended lifespan in cooperatively breeding mammals: a re-appraisal"

The influence of surrounding land cover on #Wetland habitat conditions: a case study of inland wetlands in South Korea

Mitochondrial DNA variation in the Italian Heavy Draught Horse @thePeerJ

Spirometric traits show quantile-dependent heritability, which may contribute to their gene-environment interactions with smoking and pollution @thePeerJ

Personalized analysis of breast cancer using sample-specific networks @thePeerJ