Bioinformatics and Genomics

Article commentary

Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels

Editor rating: 7 / 10

Steven Buyske –– The article shows genetics associations of lipid traits in populations (cohorts from Nigeria and the Philippines) not previously studied. Besides confirming some associations already found in Europeans, the authors found novel associations in BACE1 and SIDT2.
Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review

Editor rating: 7 / 10

Jun Pang –– It is a very interesting literature review.
Translating genomics into practice for real-time surveillance and response to carbapenemase-producing Enterobacteriaceae: evidence from a complex multi-institutional KPC outbreak

Editor rating: 9 / 10

Nicholas Loman –– This is a really well worked example of how whole genome sequencing is transforming public health surveillance of infectious diseases.
A gene expression-based risk model reveals prognosis of gastric cancer

Editor rating: 7 / 10

Yong Wang –– The authors provide a potential useful diagnostic model for gastric cancer by using omics data
Profiling soil microbial communities with next-generation sequencing: the influence of DNA kit selection and technician technical expertise

Editor rating: 7 / 10

Juan Riesgo-Escovar –– It addresses methodological problems that hinder comparison of these type of results from different publications.
Simulations indicate that scores of lionfish (Pterois volitans) colonized the Atlantic Ocean

Editor rating: 7 / 10

Mark Hixon –– This study provides insight on the size of the founding introduced population that gave rise to one of the worst marine invasions in history.
Genome-wide identification of ABA receptor PYL family and expression analysis of PYLs in response to ABA and osmotic stress in Gossypium

Editor rating: 10 / 10

Pankaj Jaiswal –– It contributes to PYL gene family annotation in cotton.
A microbial survey of the International Space Station (ISS)

Editor rating: 9 / 10

Joël Mossong –– This is an interesting article on the microbial contamination of an unusual habitat in space, the international space station.
Development of medical informatics in China over the past 30 years from a conference perspective and a Sino-American comparison

Editor rating: 8 / 10

Yuriy Orlov –– It raises new questions on global influence on science, and cross-country science competition. In this case in medical informatics.
Uncovering the relationship and mechanisms of Tartary buckwheat (Fagopyrum tataricum) and Type II diabetes, hypertension, and hyperlipidemia using a network pharmacology approach

Editor rating: 9 / 10

Juan Rodriguez-Flores –– While many different studies compare diets on a broad level in terms of their impact on T2D, this study takes a unique approach and looks at a particular food (buckwheat) in terms of its biochemical composition and the medicinal value of each compound. This is a valuable approach that should be conducted extensively for other foods with presumable medicinal value, i.e. non-pharmaceutical risk reduction or treatment of disease.

Discussing these articles

Our @NIHR15 funded article on cholesterol traits in diverse populations, led by @LoyolaBioinfo BS/MS student Angela Andaleon, has been published today in @thePeerJ

Our article has been published today in @thePeerJ Well done Abby Peters - another PhD output! @livuniAgeing @livunieng #Bioengineering #Biotechnology #ComputationalBiology

263 days ago
Our paper on WGS to inform the public health response to a complex state-wide KPC outbreak in @thePeerJ with @BenjaminHowden @tstinear @torstenseemann and many others

Ever wonder how many lionfish spawned the invasion in the Atlantic? Probably over 100!

Profiling soil microbial communities with next-generation sequencing: the influence of DNA kit selection and technician technical expertise

A microbial survey of the ISS. via @thePeerJ

305 days ago
Four way #VennDiagram caught my eye in @thePeerJ email, expected #DataViz disaster, but turns out it not that bad a choice as the set overlaps here are relatively small

Discover Magazine: Dozens—Perhaps Even Hundreds—of Lionfish Likely Launched the Atlantic Invasion

Popular Science: "Scientists are trying to figure out which bacteria have colonized our space station"

The space station is about as sanitary as your run-of-the-mill bachelor pad

The International Space Station is super germy

The International Space Station is swarming with bacteria

Just Like Home: Space Station Has Same Microbes As Your House

The ISS Bacterial Community Resembles What You'd Find in Your Home

International Space Station colonised by mysterious bugs – including ‘alien’ bacteria

'Diverse' bacteria found on International Space Station like that on Earth, scientists reveal

The bacterial community on the International Space Station resembles homes