Editor rating: 7 / 10Alfonso Valencia –– The article is study of the potential functional importance of differentially expressed Circular RNAs in a particular biological system, i.e response to radiation in HeLa cells. Function is investigated in terms of enrichment in Gene Ontology and KEGG pathways. The study is representative of a general class of functional studies of biological systems combining experimental determination and functional enrichment.
Editor rating: 7 / 10Bettina Böttcher –– Nice method.
Editor rating: 7 / 10Daniel Lahr –– There really are very few pieces of software that focus on analyses of large gene families. The issue is a complicated one, and the scarcity of software actually represents the attitude of researchers to shy away from such questions. If well accepted, this has the potential to spur new ways of looking at old questions.
Editor rating: 7 / 10J. Thomas Sanderson –– Good, solid and timely review of the entitled topic.
Editor rating: 8 / 10Anthony Amend –– This paper highlights the use of a synthetic mock community as a standard to filter out bad quality data.
Section Editor rating: 7 / 10Elena Papaleo –– A nice tool to improve taxonomic classifications
Section Editor rating: 7 / 10Elena Papaleo –– An interesting comprehensive text mining approach to annotate genes
Editor rating: 7 / 10Thomas Tullius –– This clearly written paper addresses an important issue in understanding the stability of the genetic code: how frameshift mutations are accommodated.
Section Editor rating: 7 / 10Elena Papaleo –– An interesting machine learning application to enzyme classification at the structural level.
Section Editor rating: 7 / 10Elena Papaleo –– The program FluxPyt is user-friendly and help the analyses of metabolic flux.
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