Bioinformatics and Genomics

Identification and characterization of the cytosine-5 DNA methyltransferase gene family in Salvia miltiorrhiza

Editor rating: 7 / 10

Gerrit Beemster –– Epigenetic regulation is rapidly becoming a new regulatory mechanism in developmental processes and this study is a nice contribution to that field using a non model species.
Comparative genomic analysis of a new tellurite-resistant Psychrobacter strain isolated from the Antarctic Peninsula

Editor rating: 7 / 10

Tatiana Vishnivetskaya –– Metal resistant strain from cold environments could be useful for bioremediation at low temperatures
A bibliometric analysis in gene research of myocardial infarction from 2001 to 2015

Editor rating: 7 / 10

Maria Cristina Albertini –– Important information has been disclosed in the paper.
A simple molecular technique for distinguishing species reveals frequent misidentification of Hawaiian corals in the genus Pocillopora

Editor rating: 8 / 10

Xavier Pochon –– This study developed a simple and cost-effective assay that quickly allows for discrimination amongst coral species in the genus Pocillopora using simple PCR amplification followed by digestion with widely available restriction enzymes. Pocilloporid corals exhibit extreme phenotypic plasticity, making morphological identification of species very challenging. The assay was tested on 691 coral samples collected from across the Hawaiian Archipelago and successfully characterised all six Pocillopora species occurring in Hawaii. Compared to sequence-based identification, this method is simple, rapid and represents a cost saving of nearly 95%. This work will benefit future studies of population structure, ecology, biodiversity, evolution and conservation in this challenging coral genus.
Differential gene expression during early development in recently evolved and sympatric Arctic charr morphs

Editor rating: 7 / 10

Marc Robinson-Rechavi –– This study allows to link natural variation in morphology with genetic divergence in expression patterns, thus helping link ecology to molecular genomics.
An Indo-Pacific damselfish (Neopomacentrus cyanomos) in the Gulf of Mexico: origin and mode of introduction

Editor rating: 7 / 10

Donald Kramer –– Although only dealing with a single invasive species, it is a very thorough and interesting analysis of the potential for oil rigs to move fish (and potentially other marine species) around the world.
Complex versus simple models: ion-channel cardiac toxicity prediction

Editor rating: 8 / 10

Heiko Enderling –– This article discusses the contributions of quantitative models in predicting biology, and makes an important point about the balance of simplicity/complexity/accuracy/usefulness of biophysical models. If simple models capture biological complexity, the use of more detailed models must be properly justified.
Evaluating the adaptive evolutionary convergence of carnivorous plant taxa through functional genomics

Editor rating: 8 / 10

Todd Vision –– This is a novel and innovative approach to studying the genomic correlates of convergent evolution. It is likely to inspire similar studies in other systems and for other kinds of genomic changes, as well as bioinformatic work to refine and extend the methods.
Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels

Editor rating: 7 / 10

Steven Buyske –– The article shows genetics associations of lipid traits in populations (cohorts from Nigeria and the Philippines) not previously studied. Besides confirming some associations already found in Europeans, the authors found novel associations in BACE1 and SIDT2.
Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review

Editor rating: 7 / 10

Jun Pang –– It is a very interesting literature review.

Discussing these articles

Comparative genomic analysis of a new tellurite-resistant Psychrobacter strain isolated from the Antarctic Peninsula https://t.co/Pe0VoMrmWT

Zhou H, Tan W, Qiu Z, Song Y, Gao S. (2018) A bibliometric analysis in gene research of myocardial infarction from 2001 to 2015. PeerJ 6:e4354 https://t.co/DLzmzAy7tn #CiteSpace https://t.co/9IFzDlxMK6

New paper to ID Pocillopora corals https://t.co/It92AVvX7X

Differential gene expression during early development in recently evolved and sympatric Arctic charr morphs Good job @vonStadarhraun https://t.co/SKVXoWQ3Ix via @thePeerJ

new publication: https://t.co/MONo6omrX3 a comprehensive analysis on how a well-defined simple heuristic is as good (if not better) than complex mathematical models, used by FDA and bloated pharma companies, in ion-channel safety pharmacology #mathbiology

114 days ago
Evaluating the adaptive evolutionary convergence of carnivorous plant taxa through functional genomics https://t.co/z1sFqYaSeP

Our @NIHR15 funded article on cholesterol traits in diverse populations, led by @LoyolaBioinfo BS/MS student Angela Andaleon, has been published today in @thePeerJ https://t.co/3Ulwm5nvDD

Our article has been published today in @thePeerJ https://t.co/xsVSirvY3c. Well done Abby Peters - another PhD output! @livuniAgeing @livunieng #Bioengineering #Biotechnology #ComputationalBiology